(3R,6S,9E)-14-(1-hydroxy-4-methyldecan-3-yl)-6-methyl-11-methylidene-3-propan-2-yl-1-oxa-4,7,12-triazacyclotetradec-9-ene-2,5,8,13-tetrone

Details

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Internal ID 992c1a97-aad7-4178-bb62-b276b7151326
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name (3R,6S,9E)-14-(1-hydroxy-4-methyldecan-3-yl)-6-methyl-11-methylidene-3-propan-2-yl-1-oxa-4,7,12-triazacyclotetradec-9-ene-2,5,8,13-tetrone
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C26H43N3O6/c1-7-8-9-10-11-17(4)20(14-15-30)23-25(33)27-18(5)12-13-21(31)28-19(6)24(32)29-22(16(2)3)26(34)35-23/h12-13,16-17,19-20,22-23,30H,5,7-11,14-15H2,1-4,6H3,(H,27,33)(H,28,31)(H,29,32)/b13-12+/t17?,19-,20?,22+,23?/m0/s1
InChI Key QWBWNXCMGNCVQC-OIXFFAKGSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C26H43N3O6
Molecular Weight 493.60 g/mol
Exact Mass 493.31518610 g/mol
Topological Polar Surface Area (TPSA) 134.00 Ų
XlogP 4.70

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of (3R,6S,9E)-14-(1-hydroxy-4-methyldecan-3-yl)-6-methyl-11-methylidene-3-propan-2-yl-1-oxa-4,7,12-triazacyclotetradec-9-ene-2,5,8,13-tetrone

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL253 P34972 Cannabinoid CB2 receptor 99.10% 97.25%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.06% 96.09%
CHEMBL2581 P07339 Cathepsin D 95.01% 98.95%
CHEMBL3892 Q99500 Sphingosine 1-phosphate receptor Edg-3 94.89% 97.29%
CHEMBL5103 Q969S8 Histone deacetylase 10 93.10% 90.08%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 92.62% 92.88%
CHEMBL299 P17252 Protein kinase C alpha 92.53% 98.03%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 91.39% 91.11%
CHEMBL2996 Q05655 Protein kinase C delta 91.02% 97.79%
CHEMBL3060 Q9Y345 Glycine transporter 2 90.80% 99.17%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 89.34% 90.71%
CHEMBL1949 P62937 Cyclophilin A 89.01% 98.57%
CHEMBL3310 Q96DB2 Histone deacetylase 11 88.04% 88.56%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 87.47% 100.00%
CHEMBL3359 P21462 Formyl peptide receptor 1 86.70% 93.56%
CHEMBL1937 Q92769 Histone deacetylase 2 86.44% 94.75%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 86.01% 94.45%
CHEMBL3401 O75469 Pregnane X receptor 85.96% 94.73%
CHEMBL218 P21554 Cannabinoid CB1 receptor 84.89% 96.61%
CHEMBL2885 P07451 Carbonic anhydrase III 84.46% 87.45%
CHEMBL1907 P15144 Aminopeptidase N 84.22% 93.31%
CHEMBL3230 O95977 Sphingosine 1-phosphate receptor Edg-6 84.02% 94.01%
CHEMBL2563 Q9UQL6 Histone deacetylase 5 83.86% 89.67%
CHEMBL2955 O95136 Sphingosine 1-phosphate receptor Edg-5 83.64% 92.86%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 83.48% 96.47%
CHEMBL2265 P23141 Acyl coenzyme A:cholesterol acyltransferase 83.30% 85.94%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 83.06% 95.56%
CHEMBL2001 Q9H244 Purinergic receptor P2Y12 82.46% 96.00%
CHEMBL4072 P07858 Cathepsin B 82.37% 93.67%
CHEMBL4227 P25090 Lipoxin A4 receptor 82.03% 100.00%
CHEMBL1977 P11473 Vitamin D receptor 81.94% 99.43%
CHEMBL5043 Q6P179 Endoplasmic reticulum aminopeptidase 2 81.84% 91.81%
CHEMBL3137262 O60341 LSD1/CoREST complex 81.58% 97.09%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 80.97% 96.90%
CHEMBL4462 Q8IXJ6 NAD-dependent deacetylase sirtuin 2 80.63% 90.24%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139583249
LOTUS LTS0219847
wikiData Q75057861