Actinorhodin

Details

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Internal ID ee887837-dac3-486c-8430-430bab3442d4
Taxonomy Phenylpropanoids and polyketides > Isochromanequinones
IUPAC Name 2-[(1R,3S)-8-[(1R,3S)-3-(carboxymethyl)-5,6,9,10-tetrahydroxy-1-methyl-3,4-dihydro-1H-benzo[g]isochromen-8-yl]-1-methyl-5,6,9,10-tetraoxo-3,4-dihydro-1H-benzo[g]isochromen-3-yl]acetic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C32H26O14/c1-9-21-15(3-11(45-9)5-19(35)36)29(41)23-17(33)7-13(27(39)25(23)31(21)43)14-8-18(34)24-26(28(14)40)32(44)22-10(2)46-12(6-20(37)38)4-16(22)30(24)42/h7-12,33,39,41,43H,3-6H2,1-2H3,(H,35,36)(H,37,38)/t9-,10-,11+,12+/m1/s1
InChI Key MGFJRQUGYNFFDQ-WYUUTHIRSA-N
Popularity 445 references in papers

Physical and Chemical Properties

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Molecular Formula C32H26O14
Molecular Weight 634.50 g/mol
Exact Mass 634.13225550 g/mol
Topological Polar Surface Area (TPSA) 242.00 Ų
XlogP 1.90

Synonyms

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Actinorhodine
1397-77-9
G4HH387T6Z
(8,8'-Bi-1H-naphtho(2,3-c)pyran)-3,3'-diacetic acid, 3,3',4,4',5,5',10,10'-octahydro-6,6',9,9'-tetrahydroxy-1,1'-dimethyl-5,5',10,10'-tetraoxo-, (1R,1'R,3S,3'S)-
2,2'-[(1r,1'r,3s,3's)-6,6',9,9'-Tetrahydroxy-1,1'-Dimethyl-5,5',10,10'-Tetraoxo-3,3',4,4',5,5',10,10'-Octahydro-1h,1'h-8,8'-Bibenzo[g]isochromene-3,3'-Diyl]diacetic Acid
UNII-G4HH387T6Z
ACTINORHODINE [MI]
SCHEMBL95607
CHEBI:2448
SCHEMBL1177648
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

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2D Structure of Actinorhodin

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.35% 91.11%
CHEMBL2581 P07339 Cathepsin D 97.32% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 91.29% 96.09%
CHEMBL1806 P11388 DNA topoisomerase II alpha 90.21% 89.00%
CHEMBL3401 O75469 Pregnane X receptor 89.50% 94.73%
CHEMBL1293249 Q13887 Kruppel-like factor 5 87.87% 86.33%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 87.27% 95.56%
CHEMBL221 P23219 Cyclooxygenase-1 87.23% 90.17%
CHEMBL1951 P21397 Monoamine oxidase A 86.89% 91.49%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 86.64% 90.71%
CHEMBL3060 Q9Y345 Glycine transporter 2 86.27% 99.17%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 85.85% 85.14%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 84.42% 99.15%
CHEMBL2094127 P06493 Cyclin-dependent kinase 1/cyclin B 81.01% 96.00%
CHEMBL4208 P20618 Proteasome component C5 81.01% 90.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 441143
LOTUS LTS0121050
wikiData Q76100199