Acremolide B

Details

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Internal ID d5ec5a1b-bafe-42d9-83ca-b318a7a4da2d
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name (3R,12S)-3-benzyl-7-hydroxy-6-methyl-9-(7-oxooctan-2-yl)-10-oxa-1,4-diazabicyclo[10.3.0]pentadecane-2,5,11-trione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C28H40N2O6/c1-18(10-7-8-11-19(2)31)25-17-24(32)20(3)26(33)29-22(16-21-12-5-4-6-13-21)27(34)30-15-9-14-23(30)28(35)36-25/h4-6,12-13,18,20,22-25,32H,7-11,14-17H2,1-3H3,(H,29,33)/t18?,20?,22-,23+,24?,25?/m1/s1
InChI Key AOQQOEQINNPMNK-HJZYFBBOSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C28H40N2O6
Molecular Weight 500.60 g/mol
Exact Mass 500.28863700 g/mol
Topological Polar Surface Area (TPSA) 113.00 Ų
XlogP 3.30

Synonyms

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CHEMBL401952

2D Structure

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2D Structure of Acremolide B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.69% 98.95%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 98.51% 85.14%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.33% 96.09%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 96.29% 97.64%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 94.64% 91.11%
CHEMBL1902 P62942 FK506-binding protein 1A 94.22% 97.05%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.12% 95.56%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 92.21% 93.00%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 90.44% 82.38%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 89.06% 94.45%
CHEMBL5608 Q16288 NT-3 growth factor receptor 88.94% 95.89%
CHEMBL5103 Q969S8 Histone deacetylase 10 88.60% 90.08%
CHEMBL253 P34972 Cannabinoid CB2 receptor 87.81% 97.25%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 87.13% 99.23%
CHEMBL3137262 O60341 LSD1/CoREST complex 86.70% 97.09%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 85.88% 95.50%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 85.18% 93.03%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 84.19% 98.33%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 84.06% 90.71%
CHEMBL3060 Q9Y345 Glycine transporter 2 83.15% 99.17%
CHEMBL1806 P11388 DNA topoisomerase II alpha 82.06% 89.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 81.11% 86.33%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 81.09% 96.47%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 24853812
LOTUS LTS0238847
wikiData Q77385557