Acremolactone B

Details

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Internal ID 56f02383-5153-4432-9d70-4ad318c2d432
Taxonomy Organoheterocyclic compounds > Pyridines and derivatives > Phenylpyridines
IUPAC Name (6S,6aS,9S,9aS)-4,6-dihydroxy-9-[(E,1S)-1-hydroxy-2-methylhex-2-enyl]-6a-methyl-3-(2-methylphenyl)-5,6,9,9a-tetrahydrofuro[2,3-h]isoquinolin-8-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C26H31NO5/c1-5-6-9-15(3)23(29)20-21-18-13-27-22(16-11-8-7-10-14(16)2)24(30)17(18)12-19(28)26(21,4)32-25(20)31/h7-11,13,19-21,23,28-30H,5-6,12H2,1-4H3/b15-9+/t19-,20-,21+,23+,26+/m0/s1
InChI Key PGFXNTBJNUFXCN-YRANEMMESA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C26H31NO5
Molecular Weight 437.50 g/mol
Exact Mass 437.22022309 g/mol
Topological Polar Surface Area (TPSA) 99.90 Ų
XlogP 4.30

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Acremolactone B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.49% 98.95%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.32% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 93.88% 96.09%
CHEMBL1806 P11388 DNA topoisomerase II alpha 93.67% 89.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 93.55% 86.33%
CHEMBL1293267 Q9HC97 G-protein coupled receptor 35 92.38% 89.34%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 91.57% 95.56%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 90.97% 99.23%
CHEMBL1937 Q92769 Histone deacetylase 2 90.97% 94.75%
CHEMBL3060 Q9Y345 Glycine transporter 2 90.63% 99.17%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 89.21% 85.14%
CHEMBL3401 O75469 Pregnane X receptor 87.62% 94.73%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 86.05% 96.47%
CHEMBL3359 P21462 Formyl peptide receptor 1 85.84% 93.56%
CHEMBL3524 P56524 Histone deacetylase 4 85.68% 92.97%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 82.87% 93.40%
CHEMBL1944495 P28065 Proteasome subunit beta type-9 82.75% 97.50%
CHEMBL5103 Q969S8 Histone deacetylase 10 82.27% 90.08%
CHEMBL4040 P28482 MAP kinase ERK2 81.95% 83.82%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 81.40% 96.00%
CHEMBL1907 P15144 Aminopeptidase N 80.37% 93.31%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 80.35% 90.71%
CHEMBL2535 P11166 Glucose transporter 80.28% 98.75%
CHEMBL5608 Q16288 NT-3 growth factor receptor 80.04% 95.89%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 101371652
LOTUS LTS0077181
wikiData Q75064488