Ac-Phe-Aib-Aib-Aib-D-Iva-Gly-Leu-D-Iva-Aib-Hyp-Gln-D-Iva-Hyp-Aib-Pro-D-Phe-ol

Details

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Internal ID b577a2a2-ed8b-46d1-99e7-be5baab66025
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides > Oligopeptides
IUPAC Name (2S)-2-[[(2S,4R)-1-[2-[[(2R)-2-[[(2S)-2-[[2-[[(2R)-2-[[2-[[2-[[2-[[(2S)-2-acetamido-3-phenylpropanoyl]amino]-2-methylpropanoyl]amino]-2-methylpropanoyl]amino]-2-methylpropanoyl]amino]-2-methylbutanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-2-methylbutanoyl]amino]-2-methylpropanoyl]-4-hydroxypyrrolidine-2-carbonyl]amino]-N-[(2R)-1-[(2S,4R)-4-hydroxy-2-[[1-[(2S)-2-[[(2R)-1-hydroxy-3-phenylpropan-2-yl]carbamoyl]pyrrolidin-1-yl]-2-methyl-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-2-methyl-1-oxobutan-2-yl]pentanediamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C83H129N17O20/c1-20-81(17,97-70(115)78(11,12)95-69(114)77(9,10)94-68(113)76(7,8)90-63(108)56(86-48(6)102)40-50-32-27-24-28-33-50)71(116)85-43-61(106)88-55(38-47(4)5)64(109)92-82(18,21-2)72(117)96-80(15,16)74(119)99-44-52(103)41-58(99)66(111)89-54(35-36-60(84)105)62(107)93-83(19,22-3)75(120)100-45-53(104)42-59(100)67(112)91-79(13,14)73(118)98-37-29-34-57(98)65(110)87-51(46-101)39-49-30-25-23-26-31-49/h23-28,30-33,47,51-59,101,103-104H,20-22,29,34-46H2,1-19H3,(H2,84,105)(H,85,116)(H,86,102)(H,87,110)(H,88,106)(H,89,111)(H,90,108)(H,91,112)(H,92,109)(H,93,107)(H,94,113)(H,95,114)(H,96,117)(H,97,115)/t51-,52-,53-,54+,55+,56+,57+,58+,59+,81-,82-,83-/m1/s1
InChI Key DGKRSIOCIYNNHE-UTJIKYAXSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C83H129N17O20
Molecular Weight 1685.00 g/mol
Exact Mass 1683.95997957 g/mol
Topological Polar Surface Area (TPSA) 543.00 Ų
XlogP 0.50

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Ac-Phe-Aib-Aib-Aib-D-Iva-Gly-Leu-D-Iva-Aib-Hyp-Gln-D-Iva-Hyp-Aib-Pro-D-Phe-ol

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.92% 98.95%
CHEMBL3837 P07711 Cathepsin L 99.47% 96.61%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.01% 96.09%
CHEMBL220 P22303 Acetylcholinesterase 98.56% 94.45%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 98.35% 98.33%
CHEMBL221 P23219 Cyclooxygenase-1 98.15% 90.17%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 97.72% 97.14%
CHEMBL4394 Q9NYA1 Sphingosine kinase 1 96.75% 96.03%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 96.28% 82.69%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 96.03% 97.64%
CHEMBL340 P08684 Cytochrome P450 3A4 95.79% 91.19%
CHEMBL1914 P06276 Butyrylcholinesterase 95.50% 95.00%
CHEMBL3359 P21462 Formyl peptide receptor 1 95.07% 93.56%
CHEMBL259 P32245 Melanocortin receptor 4 94.79% 95.38%
CHEMBL3137262 O60341 LSD1/CoREST complex 94.56% 97.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 94.41% 91.11%
CHEMBL4227 P25090 Lipoxin A4 receptor 92.69% 100.00%
CHEMBL2514 O95665 Neurotensin receptor 2 91.99% 100.00%
CHEMBL4018 P49146 Neuropeptide Y receptor type 2 90.94% 98.94%
CHEMBL1907594 P30926 Neuronal acetylcholine receptor; alpha3/beta4 90.73% 97.23%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 90.52% 93.00%
CHEMBL1944495 P28065 Proteasome subunit beta type-9 90.27% 97.50%
CHEMBL4123 P30989 Neurotensin receptor 1 89.99% 96.67%
CHEMBL1255126 O15151 Protein Mdm4 89.64% 90.20%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 89.63% 100.00%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 89.55% 95.56%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 88.54% 96.00%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 88.18% 96.47%
CHEMBL5939 Q9NZ08 Endoplasmic reticulum aminopeptidase 1 87.65% 100.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 87.49% 95.89%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 87.40% 95.50%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 87.16% 90.71%
CHEMBL5701 Q9H2K8 Serine/threonine-protein kinase TAO3 87.10% 96.67%
CHEMBL2664 P23526 Adenosylhomocysteinase 85.76% 86.67%
CHEMBL2535 P11166 Glucose transporter 85.34% 98.75%
CHEMBL5043 Q6P179 Endoplasmic reticulum aminopeptidase 2 85.28% 91.81%
CHEMBL3060 Q9Y345 Glycine transporter 2 84.57% 99.17%
CHEMBL4777 P25929 Neuropeptide Y receptor type 1 84.43% 96.67%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 84.40% 95.89%
CHEMBL3024 P53350 Serine/threonine-protein kinase PLK1 84.38% 97.43%
CHEMBL5261 Q7L7X3 Serine/threonine-protein kinase TAO1 83.97% 89.33%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 83.83% 94.45%
CHEMBL253 P34972 Cannabinoid CB2 receptor 83.67% 97.25%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 82.32% 96.95%
CHEMBL3476 O15111 Inhibitor of nuclear factor kappa B kinase alpha subunit 81.92% 95.83%
CHEMBL1806 P11388 DNA topoisomerase II alpha 81.37% 89.00%
CHEMBL5028 O14672 ADAM10 81.29% 97.50%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 163059344
LOTUS LTS0097267
wikiData Q104978828