Ac-DL-xiThr(1)-DL-Phe-DL-Ala-DL-Pro-DL-Trp-(1)

Details

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Internal ID 8612ee05-160f-40bb-bc7c-badf4e28a1f0
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name N-[6-benzyl-13-(1H-indol-3-ylmethyl)-3,10-dimethyl-2,5,8,12,15-pentaoxo-11-oxa-1,4,7,14-tetrazabicyclo[14.3.0]nonadecan-9-yl]acetamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C34H40N6O7/c1-19-33(45)40-15-9-14-28(40)31(43)39-27(17-23-18-35-25-13-8-7-12-24(23)25)34(46)47-20(2)29(37-21(3)41)32(44)38-26(30(42)36-19)16-22-10-5-4-6-11-22/h4-8,10-13,18-20,26-29,35H,9,14-17H2,1-3H3,(H,36,42)(H,37,41)(H,38,44)(H,39,43)
InChI Key IACBOWBNBXRQFN-UHFFFAOYSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C34H40N6O7
Molecular Weight 644.70 g/mol
Exact Mass 644.29584764 g/mol
Topological Polar Surface Area (TPSA) 179.00 Ų
XlogP 2.30

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Ac-DL-xiThr(1)-DL-Phe-DL-Ala-DL-Pro-DL-Trp-(1)

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 99.67% 85.14%
CHEMBL2581 P07339 Cathepsin D 99.39% 98.95%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 98.32% 97.64%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.70% 91.11%
CHEMBL1951 P21397 Monoamine oxidase A 97.02% 91.49%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.14% 96.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.06% 95.56%
CHEMBL333 P08253 Matrix metalloproteinase-2 93.27% 96.31%
CHEMBL5103 Q969S8 Histone deacetylase 10 91.13% 90.08%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 90.29% 93.03%
CHEMBL1806 P11388 DNA topoisomerase II alpha 90.21% 89.00%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 89.00% 99.23%
CHEMBL4040 P28482 MAP kinase ERK2 88.71% 83.82%
CHEMBL1902 P62942 FK506-binding protein 1A 88.27% 97.05%
CHEMBL3155 P34969 Serotonin 7 (5-HT7) receptor 87.14% 90.71%
CHEMBL255 P29275 Adenosine A2b receptor 86.86% 98.59%
CHEMBL5608 Q16288 NT-3 growth factor receptor 86.00% 95.89%
CHEMBL3310 Q96DB2 Histone deacetylase 11 84.95% 88.56%
CHEMBL5805 Q9NR97 Toll-like receptor 8 84.35% 96.25%
CHEMBL3137262 O60341 LSD1/CoREST complex 84.25% 97.09%
CHEMBL3524 P56524 Histone deacetylase 4 83.11% 92.97%
CHEMBL4644 P41968 Melanocortin receptor 3 82.85% 99.52%
CHEMBL3476 O15111 Inhibitor of nuclear factor kappa B kinase alpha subunit 82.78% 95.83%
CHEMBL4531 P17931 Galectin-3 81.85% 96.90%
CHEMBL4051 P13569 Cystic fibrosis transmembrane conductance regulator 81.40% 95.71%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 163062232
LOTUS LTS0096122
wikiData Q104168556