Ac-D-Gln-Ile-N(Me)Leu-Ile-N(Me)Val-N(Me)Ile-N(Me)Ile-N(Me)Ile-OH

Details

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Internal ID 0b3157a8-ae89-4f07-9f23-e35acc71eb98
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides
IUPAC Name (2S,3S)-2-[[(2S,3S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2R)-2-acetamido-5-amino-5-oxopentanoyl]amino]-3-methylpentanoyl]-methylamino]-4-methylpentanoyl]amino]-3-methylpentanoyl]-methylamino]-3-methylbutanoyl]-methylamino]-3-methylpentanoyl]-methylamino]-3-methylpentanoyl]-methylamino]-3-methylpentanoic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C53H97N9O11/c1-21-31(10)40(56-46(65)37(55-36(15)63)26-27-39(54)64)48(67)58(16)38(28-29(6)7)47(66)57-41(32(11)22-2)49(68)59(17)42(30(8)9)50(69)60(18)43(33(12)23-3)51(70)61(19)44(34(13)24-4)52(71)62(20)45(53(72)73)35(14)25-5/h29-35,37-38,40-45H,21-28H2,1-20H3,(H2,54,64)(H,55,63)(H,56,65)(H,57,66)(H,72,73)/t31-,32-,33-,34-,35-,37+,38-,40-,41-,42-,43-,44-,45-/m0/s1
InChI Key YEHYELQIMQIGQU-VMIGUSPASA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C53H97N9O11
Molecular Weight 1036.40 g/mol
Exact Mass 1035.73075494 g/mol
Topological Polar Surface Area (TPSA) 269.00 Ų
XlogP 6.40

Synonyms

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SCHEMBL29557912
InChI=1/C53H97N9O11/c1-21-31(10)40(56-46(65)37(55-36(15)63)26-27-39(54)64)48(67)58(16)38(28-29(6)7)47(66)57-41(32(11)22-2)49(68)59(17)42(30(8)9)50(69)60(18)43(33(12)23-3)51(70)61(19)44(34(13)24-4)52(71)62(20)45(53(72)73)35(14)25-5/h29-35,37-38,40-45H,21-

2D Structure

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2D Structure of Ac-D-Gln-Ile-N(Me)Leu-Ile-N(Me)Val-N(Me)Ile-N(Me)Ile-N(Me)Ile-OH

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3837 P07711 Cathepsin L 99.37% 96.61%
CHEMBL2581 P07339 Cathepsin D 99.25% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.17% 96.09%
CHEMBL221 P23219 Cyclooxygenase-1 96.77% 90.17%
CHEMBL3359 P21462 Formyl peptide receptor 1 95.05% 93.56%
CHEMBL2094135 Q96BI3 Gamma-secretase 94.35% 98.05%
CHEMBL3060 Q9Y345 Glycine transporter 2 93.78% 99.17%
CHEMBL2514 O95665 Neurotensin receptor 2 93.15% 100.00%
CHEMBL4018 P49146 Neuropeptide Y receptor type 2 90.71% 98.94%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 90.45% 96.47%
CHEMBL340 P08684 Cytochrome P450 3A4 89.57% 91.19%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 89.47% 100.00%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 89.36% 93.00%
CHEMBL3776 Q14790 Caspase-8 87.19% 97.06%
CHEMBL3024 P53350 Serine/threonine-protein kinase PLK1 86.68% 97.43%
CHEMBL203 P00533 Epidermal growth factor receptor erbB1 86.37% 97.34%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 85.57% 96.00%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 85.18% 98.33%
CHEMBL2413 P32246 C-C chemokine receptor type 1 84.31% 89.50%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 84.01% 94.33%
CHEMBL3308 P55212 Caspase-6 83.88% 97.56%
CHEMBL4227 P25090 Lipoxin A4 receptor 83.84% 100.00%
CHEMBL2885 P07451 Carbonic anhydrase III 83.21% 87.45%
CHEMBL3004 P33527 Multidrug resistance-associated protein 1 82.87% 96.37%
CHEMBL3267 P48736 PI3-kinase p110-gamma subunit 82.49% 95.71%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 82.08% 91.11%
CHEMBL4618 P09960 Leukotriene A4 hydrolase 82.03% 97.86%
CHEMBL1255126 O15151 Protein Mdm4 81.66% 90.20%
CHEMBL5285 Q99683 Mitogen-activated protein kinase kinase kinase 5 81.59% 92.26%
CHEMBL1944495 P28065 Proteasome subunit beta type-9 80.94% 97.50%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 80.22% 90.71%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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Cross-Links

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PubChem 11665244
LOTUS LTS0121195
wikiData Q105347245