Ac-Aib-Pro-Aib-Ala-Aib-Aib-Gln-Aib-Ile-Aib-Gly-Aib-Aib-Pro-Val-Aib-Iva-Gln-Gln-Leu-ol

Details

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Internal ID 2c3a6df4-07f1-4e28-b99b-646e40845d72
Taxonomy Organic Polymers > Polypeptides
IUPAC Name (2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-1-[2-[[2-[[2-[[2-[[(2S,3S)-2-[[2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[2-[[(2S)-1-(2-acetamido-2-methylpropanoyl)pyrrolidine-2-carbonyl]amino]-2-methylpropanoyl]amino]propanoyl]amino]-2-methylpropanoyl]amino]-2-methylpropanoyl]amino]-5-amino-5-oxopentanoyl]amino]-2-methylpropanoyl]amino]-3-methylpentanoyl]amino]-2-methylpropanoyl]amino]acetyl]amino]-2-methylpropanoyl]amino]-2-methylpropanoyl]pyrrolidine-2-carbonyl]amino]-3-methylbutanoyl]amino]-2-methylpropanoyl]amino]-2-methylbutanoyl]amino]-5-amino-5-oxopentanoyl]amino]-N-[(2S)-1-hydroxy-4-methylpentan-2-yl]pentanediamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C90H155N23O24/c1-29-48(7)62(101-74(131)83(14,15)105-66(123)54(37-40-59(93)118)98-73(130)84(16,17)109-76(133)86(20,21)104-63(120)49(8)95-72(129)82(12,13)106-68(125)56-34-32-42-113(56)79(136)88(24,25)102-50(9)115)70(127)108-81(10,11)71(128)94-44-60(119)103-85(18,19)75(132)110-89(26,27)80(137)112-41-31-33-55(112)67(124)100-61(47(5)6)69(126)107-87(22,23)77(134)111-90(28,30-2)78(135)99-53(36-39-58(92)117)65(122)97-52(35-38-57(91)116)64(121)96-51(45-114)43-46(3)4/h46-49,51-56,61-62,114H,29-45H2,1-28H3,(H2,91,116)(H2,92,117)(H2,93,118)(H,94,128)(H,95,129)(H,96,121)(H,97,122)(H,98,130)(H,99,135)(H,100,124)(H,101,131)(H,102,115)(H,103,119)(H,104,120)(H,105,123)(H,106,125)(H,107,126)(H,108,127)(H,109,133)(H,110,132)(H,111,134)/t48-,49-,51-,52-,53-,54-,55-,56-,61-,62-,90-/m0/s1
InChI Key REQOIECUJNXLSU-WDMOKMKFSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C90H155N23O24
Molecular Weight 1943.30 g/mol
Exact Mass 1942.16153290 g/mol
Topological Polar Surface Area (TPSA) 714.00 Ų
XlogP -2.80

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Ac-Aib-Pro-Aib-Ala-Aib-Aib-Gln-Aib-Ile-Aib-Gly-Aib-Aib-Pro-Val-Aib-Iva-Gln-Gln-Leu-ol

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.79% 98.95%
CHEMBL3837 P07711 Cathepsin L 99.56% 96.61%
CHEMBL220 P22303 Acetylcholinesterase 99.47% 94.45%
CHEMBL4018 P49146 Neuropeptide Y receptor type 2 98.85% 98.94%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 98.80% 98.33%
CHEMBL4588 P22894 Matrix metalloproteinase 8 98.13% 94.66%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.83% 96.09%
CHEMBL1914 P06276 Butyrylcholinesterase 97.65% 95.00%
CHEMBL333 P08253 Matrix metalloproteinase-2 97.47% 96.31%
CHEMBL2815 P04629 Nerve growth factor receptor Trk-A 97.38% 87.16%
CHEMBL4625 Q07817 Apoptosis regulator Bcl-X 97.29% 99.77%
CHEMBL3359 P21462 Formyl peptide receptor 1 97.18% 93.56%
CHEMBL2514 O95665 Neurotensin receptor 2 96.95% 100.00%
CHEMBL253 P34972 Cannabinoid CB2 receptor 96.86% 97.25%
CHEMBL340 P08684 Cytochrome P450 3A4 96.40% 91.19%
CHEMBL2730 P21980 Protein-glutamine gamma-glutamyltransferase 96.33% 92.38%
CHEMBL321 P14780 Matrix metalloproteinase 9 96.10% 92.12%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 95.50% 96.47%
CHEMBL3137262 O60341 LSD1/CoREST complex 95.44% 97.09%
CHEMBL2094135 Q96BI3 Gamma-secretase 95.34% 98.05%
CHEMBL4979 P13866 Sodium/glucose cotransporter 1 95.31% 98.24%
CHEMBL335 P18031 Protein-tyrosine phosphatase 1B 95.18% 95.17%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 94.06% 100.00%
CHEMBL3024 P53350 Serine/threonine-protein kinase PLK1 94.04% 97.43%
CHEMBL4123 P30989 Neurotensin receptor 1 94.02% 96.67%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 93.74% 97.14%
CHEMBL3267 P48736 PI3-kinase p110-gamma subunit 93.67% 95.71%
CHEMBL3892 Q99500 Sphingosine 1-phosphate receptor Edg-3 93.63% 97.29%
CHEMBL4394 Q9NYA1 Sphingosine kinase 1 93.49% 96.03%
CHEMBL236 P41143 Delta opioid receptor 93.40% 99.35%
CHEMBL283 P08254 Matrix metalloproteinase 3 93.40% 97.29%
CHEMBL4777 P25929 Neuropeptide Y receptor type 1 92.90% 96.67%
CHEMBL3437 Q16853 Amine oxidase, copper containing 92.87% 94.00%
CHEMBL4227 P25090 Lipoxin A4 receptor 92.87% 100.00%
CHEMBL4005 P42336 PI3-kinase p110-alpha subunit 92.67% 97.47%
CHEMBL1944495 P28065 Proteasome subunit beta type-9 92.35% 97.50%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 92.24% 97.64%
CHEMBL259 P32245 Melanocortin receptor 4 92.08% 95.38%
CHEMBL4816 Q9Y243 Serine/threonine-protein kinase AKT3 91.97% 96.28%
CHEMBL3176 O43603 Galanin receptor 2 91.03% 98.89%
CHEMBL5600 P27448 Serine/threonine-protein kinase c-TAK1 90.95% 88.81%
CHEMBL2073 P07947 Tyrosine-protein kinase YES 90.80% 83.14%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 90.70% 82.69%
CHEMBL2664 P23526 Adenosylhomocysteinase 90.63% 86.67%
CHEMBL332 P03956 Matrix metalloproteinase-1 90.34% 94.50%
CHEMBL2492 P36544 Neuronal acetylcholine receptor protein alpha-7 subunit 90.19% 88.42%
CHEMBL206 P03372 Estrogen receptor alpha 90.11% 97.64%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 89.45% 93.00%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 88.75% 100.00%
CHEMBL3430907 Q96GD4 Aurora kinase B/Inner centromere protein 88.54% 97.50%
CHEMBL2955 O95136 Sphingosine 1-phosphate receptor Edg-5 88.50% 92.86%
CHEMBL237 P41145 Kappa opioid receptor 88.09% 98.10%
CHEMBL1873 P00750 Tissue-type plasminogen activator 87.73% 93.33%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 87.58% 94.33%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 87.52% 96.90%
CHEMBL3018 Q9Y5Y6 Matriptase 87.49% 98.33%
CHEMBL3060 Q9Y345 Glycine transporter 2 87.46% 99.17%
CHEMBL3145 P42338 PI3-kinase p110-beta subunit 87.32% 98.75%
CHEMBL1075317 P61964 WD repeat-containing protein 5 87.02% 96.33%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 86.99% 91.11%
CHEMBL1907594 P30926 Neuronal acetylcholine receptor; alpha3/beta4 86.77% 97.23%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 86.37% 96.38%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 86.18% 96.00%
CHEMBL3830 Q2M2I8 Adaptor-associated kinase 86.05% 83.10%
CHEMBL230 P35354 Cyclooxygenase-2 85.94% 89.63%
CHEMBL2534 O15530 3-phosphoinositide dependent protein kinase-1 85.75% 95.36%
CHEMBL4801 P29466 Caspase-1 85.72% 96.85%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 85.25% 95.00%
CHEMBL5701 Q9H2K8 Serine/threonine-protein kinase TAO3 85.01% 96.67%
CHEMBL3238 P23786 Carnitine palmitoyltransferase 2 84.71% 94.05%
CHEMBL2140 P48775 Tryptophan 2,3-dioxygenase 84.69% 98.46%
CHEMBL5103 Q969S8 Histone deacetylase 10 84.31% 90.08%
CHEMBL5261 Q7L7X3 Serine/threonine-protein kinase TAO1 84.03% 89.33%
CHEMBL249 P25103 Neurokinin 1 receptor 83.86% 99.17%
CHEMBL1744525 P43490 Nicotinamide phosphoribosyltransferase 83.59% 96.25%
CHEMBL3691 Q13822 Autotaxin 82.97% 96.39%
CHEMBL3105 P09874 Poly [ADP-ribose] polymerase-1 82.71% 93.90%
CHEMBL4073 P09237 Matrix metalloproteinase 7 82.69% 97.56%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 82.63% 90.71%
CHEMBL3776 Q14790 Caspase-8 82.58% 97.06%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 82.55% 92.88%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 82.39% 93.04%
CHEMBL2413 P32246 C-C chemokine receptor type 1 82.38% 89.50%
CHEMBL4660 P28907 Lymphocyte differentiation antigen CD38 82.01% 95.27%
CHEMBL5608 Q16288 NT-3 growth factor receptor 81.78% 95.89%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 81.41% 82.38%
CHEMBL4296 Q15858 Sodium channel protein type IX alpha subunit 81.41% 96.11%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 81.16% 95.50%
CHEMBL5028 O14672 ADAM10 80.79% 97.50%
CHEMBL2007625 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic 80.27% 99.00%
CHEMBL274 P51681 C-C chemokine receptor type 5 80.01% 98.77%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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Cross-Links

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PubChem 101639446
LOTUS LTS0211365
wikiData Q105235022