Ac-Aib-Pro-Aib-Ala-Aib-Aib-Gln-Aib-Ile-Aib-Gly-Aib-Aib-Pro-Val-Aib-Aib-Gln-Gln-Leu-ol

Details

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Internal ID 266ff823-eaa1-490d-81e2-31e12a6de50b
Taxonomy Organic Polymers > Polypeptides
IUPAC Name (2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S)-1-[2-[[2-[[2-[[2-[[(2S,3S)-2-[[2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[2-[[(2S)-1-(2-acetamido-2-methylpropanoyl)pyrrolidine-2-carbonyl]amino]-2-methylpropanoyl]amino]propanoyl]amino]-2-methylpropanoyl]amino]-2-methylpropanoyl]amino]-5-amino-5-oxopentanoyl]amino]-2-methylpropanoyl]amino]-3-methylpentanoyl]amino]-2-methylpropanoyl]amino]acetyl]amino]-2-methylpropanoyl]amino]-2-methylpropanoyl]pyrrolidine-2-carbonyl]amino]-3-methylbutanoyl]amino]-2-methylpropanoyl]amino]-2-methylpropanoyl]amino]-5-amino-5-oxopentanoyl]amino]-N-[(2S)-1-hydroxy-4-methylpentan-2-yl]pentanediamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C89H153N23O24/c1-29-47(6)61(100-74(131)82(13,14)104-65(122)53(36-39-58(92)117)98-73(130)84(17,18)108-76(133)86(21,22)103-62(119)48(7)94-71(128)81(11,12)105-67(124)55-33-31-41-112(55)78(135)88(25,26)101-49(8)114)69(126)107-80(9,10)70(127)93-43-59(118)102-85(19,20)75(132)110-89(27,28)79(136)111-40-30-32-54(111)66(123)99-60(46(4)5)68(125)106-87(23,24)77(134)109-83(15,16)72(129)97-52(35-38-57(91)116)64(121)96-51(34-37-56(90)115)63(120)95-50(44-113)42-45(2)3/h45-48,50-55,60-61,113H,29-44H2,1-28H3,(H2,90,115)(H2,91,116)(H2,92,117)(H,93,127)(H,94,128)(H,95,120)(H,96,121)(H,97,129)(H,98,130)(H,99,123)(H,100,131)(H,101,114)(H,102,118)(H,103,119)(H,104,122)(H,105,124)(H,106,125)(H,107,126)(H,108,133)(H,109,134)(H,110,132)/t47-,48-,50-,51-,52-,53-,54-,55-,60-,61-/m0/s1
InChI Key SLKNUWYCNCMUDU-IBZHQNROSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C89H153N23O24
Molecular Weight 1929.30 g/mol
Exact Mass 1928.14588284 g/mol
Topological Polar Surface Area (TPSA) 714.00 Ų
XlogP -3.30

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Ac-Aib-Pro-Aib-Ala-Aib-Aib-Gln-Aib-Ile-Aib-Gly-Aib-Aib-Pro-Val-Aib-Aib-Gln-Gln-Leu-ol

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.79% 98.95%
CHEMBL3837 P07711 Cathepsin L 99.64% 96.61%
CHEMBL4018 P49146 Neuropeptide Y receptor type 2 98.86% 98.94%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 98.80% 98.33%
CHEMBL220 P22303 Acetylcholinesterase 98.61% 94.45%
CHEMBL4588 P22894 Matrix metalloproteinase 8 98.24% 94.66%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.87% 96.09%
CHEMBL333 P08253 Matrix metalloproteinase-2 97.58% 96.31%
CHEMBL253 P34972 Cannabinoid CB2 receptor 97.31% 97.25%
CHEMBL3359 P21462 Formyl peptide receptor 1 97.18% 93.56%
CHEMBL2730 P21980 Protein-glutamine gamma-glutamyltransferase 96.95% 92.38%
CHEMBL2514 O95665 Neurotensin receptor 2 96.89% 100.00%
CHEMBL2815 P04629 Nerve growth factor receptor Trk-A 96.67% 87.16%
CHEMBL1914 P06276 Butyrylcholinesterase 96.55% 95.00%
CHEMBL340 P08684 Cytochrome P450 3A4 96.29% 91.19%
CHEMBL4625 Q07817 Apoptosis regulator Bcl-X 95.96% 99.77%
CHEMBL3137262 O60341 LSD1/CoREST complex 95.53% 97.09%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 95.50% 96.47%
CHEMBL335 P18031 Protein-tyrosine phosphatase 1B 95.46% 95.17%
CHEMBL2094135 Q96BI3 Gamma-secretase 95.35% 98.05%
CHEMBL321 P14780 Matrix metalloproteinase 9 95.35% 92.12%
CHEMBL4979 P13866 Sodium/glucose cotransporter 1 94.91% 98.24%
CHEMBL3024 P53350 Serine/threonine-protein kinase PLK1 94.11% 97.43%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 94.06% 100.00%
CHEMBL4123 P30989 Neurotensin receptor 1 94.00% 96.67%
CHEMBL4394 Q9NYA1 Sphingosine kinase 1 93.97% 96.03%
CHEMBL283 P08254 Matrix metalloproteinase 3 93.49% 97.29%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 93.43% 97.14%
CHEMBL4777 P25929 Neuropeptide Y receptor type 1 93.20% 96.67%
CHEMBL236 P41143 Delta opioid receptor 93.16% 99.35%
CHEMBL4816 Q9Y243 Serine/threonine-protein kinase AKT3 93.16% 96.28%
CHEMBL3437 Q16853 Amine oxidase, copper containing 93.07% 94.00%
CHEMBL3267 P48736 PI3-kinase p110-gamma subunit 92.96% 95.71%
CHEMBL4227 P25090 Lipoxin A4 receptor 92.87% 100.00%
CHEMBL259 P32245 Melanocortin receptor 4 92.82% 95.38%
CHEMBL4005 P42336 PI3-kinase p110-alpha subunit 92.52% 97.47%
CHEMBL1944495 P28065 Proteasome subunit beta type-9 92.35% 97.50%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 92.32% 82.69%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 92.24% 97.64%
CHEMBL2492 P36544 Neuronal acetylcholine receptor protein alpha-7 subunit 91.99% 88.42%
CHEMBL2073 P07947 Tyrosine-protein kinase YES 91.89% 83.14%
CHEMBL3892 Q99500 Sphingosine 1-phosphate receptor Edg-3 91.27% 97.29%
CHEMBL3176 O43603 Galanin receptor 2 91.03% 98.89%
CHEMBL230 P35354 Cyclooxygenase-2 90.61% 89.63%
CHEMBL2664 P23526 Adenosylhomocysteinase 90.22% 86.67%
CHEMBL332 P03956 Matrix metalloproteinase-1 90.04% 94.50%
CHEMBL206 P03372 Estrogen receptor alpha 89.96% 97.64%
CHEMBL3830 Q2M2I8 Adaptor-associated kinase 89.01% 83.10%
CHEMBL2955 O95136 Sphingosine 1-phosphate receptor Edg-5 88.81% 92.86%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 88.46% 93.00%
CHEMBL3430907 Q96GD4 Aurora kinase B/Inner centromere protein 88.21% 97.50%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 87.80% 100.00%
CHEMBL237 P41145 Kappa opioid receptor 87.77% 98.10%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 87.76% 91.11%
CHEMBL1907594 P30926 Neuronal acetylcholine receptor; alpha3/beta4 87.69% 97.23%
CHEMBL3018 Q9Y5Y6 Matriptase 87.49% 98.33%
CHEMBL3060 Q9Y345 Glycine transporter 2 87.46% 99.17%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 87.45% 94.33%
CHEMBL1873 P00750 Tissue-type plasminogen activator 87.20% 93.33%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 87.15% 96.90%
CHEMBL4801 P29466 Caspase-1 87.09% 96.85%
CHEMBL5600 P27448 Serine/threonine-protein kinase c-TAK1 86.85% 88.81%
CHEMBL3145 P42338 PI3-kinase p110-beta subunit 86.30% 98.75%
CHEMBL5701 Q9H2K8 Serine/threonine-protein kinase TAO3 86.12% 96.67%
CHEMBL1075317 P61964 WD repeat-containing protein 5 86.10% 96.33%
CHEMBL5261 Q7L7X3 Serine/threonine-protein kinase TAO1 85.84% 89.33%
CHEMBL2140 P48775 Tryptophan 2,3-dioxygenase 85.38% 98.46%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 85.08% 96.00%
CHEMBL2534 O15530 3-phosphoinositide dependent protein kinase-1 84.86% 95.36%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 84.81% 96.95%
CHEMBL3238 P23786 Carnitine palmitoyltransferase 2 84.71% 94.05%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 84.50% 96.38%
CHEMBL1744525 P43490 Nicotinamide phosphoribosyltransferase 84.00% 96.25%
CHEMBL249 P25103 Neurokinin 1 receptor 83.86% 99.17%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 83.71% 97.21%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 83.60% 95.00%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 83.23% 92.88%
CHEMBL3105 P09874 Poly [ADP-ribose] polymerase-1 82.78% 93.90%
CHEMBL5103 Q969S8 Histone deacetylase 10 82.65% 90.08%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 82.63% 90.71%
CHEMBL3776 Q14790 Caspase-8 82.21% 97.06%
CHEMBL4073 P09237 Matrix metalloproteinase 7 82.03% 97.56%
CHEMBL4660 P28907 Lymphocyte differentiation antigen CD38 82.01% 95.27%
CHEMBL274 P51681 C-C chemokine receptor type 5 81.95% 98.77%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 81.94% 82.38%
CHEMBL5028 O14672 ADAM10 81.87% 97.50%
CHEMBL5608 Q16288 NT-3 growth factor receptor 81.61% 95.89%
CHEMBL2413 P32246 C-C chemokine receptor type 1 81.59% 89.50%
CHEMBL4296 Q15858 Sodium channel protein type IX alpha subunit 80.94% 96.11%
CHEMBL221 P23219 Cyclooxygenase-1 80.61% 90.17%
CHEMBL3691 Q13822 Autotaxin 80.58% 96.39%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 80.52% 93.04%
CHEMBL2007625 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic 80.52% 99.00%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 80.23% 94.45%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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Cross-Links

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PubChem 101290468
LOTUS LTS0135837
wikiData Q105255384