Aspereline E

Details

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Internal ID 6724b901-4e10-4cbc-9b75-689563e2c0a0
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides > Oligopeptides
IUPAC Name (2S,3S)-2-[[2-[[(2S)-2-[[2-[(2-acetamido-2-methylpropanoyl)amino]-2-methylpropanoyl]amino]-3-methylbutanoyl]amino]-2-methylpropanoyl]amino]-N-[1-[[1-[[(2S)-3-hydroxy-1-[[1-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-2-methyl-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-2-methyl-1-oxopropan-2-yl]amino]-2-methyl-1-oxopropan-2-yl]-3-methylpentanamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C45H80N10O12/c1-18-25(4)30(48-35(63)40(6,7)51-32(60)29(24(2)3)47-36(64)42(10,11)53-37(65)43(12,13)49-26(5)58)33(61)52-44(14,15)38(66)54-41(8,9)34(62)46-28(23-57)31(59)50-45(16,17)39(67)55-21-19-20-27(55)22-56/h24-25,27-30,56-57H,18-23H2,1-17H3,(H,46,62)(H,47,64)(H,48,63)(H,49,58)(H,50,59)(H,51,60)(H,52,61)(H,53,65)(H,54,66)/t25-,27-,28-,29-,30-/m0/s1
InChI Key RSDUGRUZONMYBE-BJNPORTCSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C45H80N10O12
Molecular Weight 953.20 g/mol
Exact Mass 952.59571803 g/mol
Topological Polar Surface Area (TPSA) 323.00 Ų
XlogP -0.30

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Aspereline E

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.00% 98.95%
CHEMBL3837 P07711 Cathepsin L 98.50% 96.61%
CHEMBL253 P34972 Cannabinoid CB2 receptor 97.86% 97.25%
CHEMBL4072 P07858 Cathepsin B 97.15% 93.67%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 95.43% 98.33%
CHEMBL4588 P22894 Matrix metalloproteinase 8 95.34% 94.66%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.05% 96.09%
CHEMBL4394 Q9NYA1 Sphingosine kinase 1 94.40% 96.03%
CHEMBL333 P08253 Matrix metalloproteinase-2 92.82% 96.31%
CHEMBL4801 P29466 Caspase-1 92.46% 96.85%
CHEMBL3359 P21462 Formyl peptide receptor 1 92.21% 93.56%
CHEMBL340 P08684 Cytochrome P450 3A4 92.11% 91.19%
CHEMBL3437 Q16853 Amine oxidase, copper containing 92.09% 94.00%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 90.67% 97.21%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 90.50% 96.95%
CHEMBL2514 O95665 Neurotensin receptor 2 88.43% 100.00%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 87.79% 93.04%
CHEMBL4018 P49146 Neuropeptide Y receptor type 2 87.33% 98.94%
CHEMBL1873 P00750 Tissue-type plasminogen activator 87.07% 93.33%
CHEMBL3137262 O60341 LSD1/CoREST complex 86.95% 97.09%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 86.85% 96.47%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 86.65% 100.00%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 86.35% 97.14%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 86.03% 94.33%
CHEMBL3691 Q13822 Autotaxin 85.99% 96.39%
CHEMBL4979 P13866 Sodium/glucose cotransporter 1 85.55% 98.24%
CHEMBL2140 P48775 Tryptophan 2,3-dioxygenase 85.37% 98.46%
CHEMBL3468 P55210 Caspase-7 85.36% 95.68%
CHEMBL4227 P25090 Lipoxin A4 receptor 85.34% 100.00%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 84.43% 100.00%
CHEMBL4073 P09237 Matrix metalloproteinase 7 84.20% 97.56%
CHEMBL1907602 P06493 Cyclin-dependent kinase 1/cyclin B1 84.15% 91.24%
CHEMBL5203 P33316 dUTP pyrophosphatase 83.97% 99.18%
CHEMBL3430907 Q96GD4 Aurora kinase B/Inner centromere protein 83.18% 97.50%
CHEMBL1944495 P28065 Proteasome subunit beta type-9 83.12% 97.50%
CHEMBL3145 P42338 PI3-kinase p110-beta subunit 83.11% 98.75%
CHEMBL2781 P19634 Sodium/hydrogen exchanger 1 82.82% 90.24%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 81.91% 94.45%
CHEMBL4015 P41597 C-C chemokine receptor type 2 81.69% 98.57%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 81.49% 96.90%
CHEMBL5608 Q16288 NT-3 growth factor receptor 81.31% 95.89%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 81.11% 90.71%
CHEMBL2955 O95136 Sphingosine 1-phosphate receptor Edg-5 80.54% 92.86%
CHEMBL283 P08254 Matrix metalloproteinase 3 80.02% 97.29%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 44178749
LOTUS LTS0080296
wikiData Q77573636