Ac-Aib-Aib-DL-Val-Aib-DL-xiIle-Aib-DL-Ala-DL-Ala-Aib-DL-Pro-ol

Details

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Internal ID 95ca2335-6186-4813-a7b4-4fd491e8e173
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides
IUPAC Name 2-[[2-[[2-[[2-[(2-acetamido-2-methylpropanoyl)amino]-2-methylpropanoyl]amino]-3-methylbutanoyl]amino]-2-methylpropanoyl]amino]-N-[1-[[1-[[1-[[1-[2-(hydroxymethyl)pyrrolidin-1-yl]-2-methyl-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-2-methyl-1-oxopropan-2-yl]-3-methylpentanamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C44H78N10O11/c1-18-24(4)30(48-36(62)41(10,11)51-33(59)29(23(2)3)47-37(63)42(12,13)53-38(64)43(14,15)49-27(7)56)34(60)52-40(8,9)35(61)46-25(5)31(57)45-26(6)32(58)50-44(16,17)39(65)54-21-19-20-28(54)22-55/h23-26,28-30,55H,18-22H2,1-17H3,(H,45,57)(H,46,61)(H,47,63)(H,48,62)(H,49,56)(H,50,58)(H,51,59)(H,52,60)(H,53,64)
InChI Key HZQUHROMJDWEGY-UHFFFAOYSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C44H78N10O11
Molecular Weight 923.20 g/mol
Exact Mass 922.58515334 g/mol
Topological Polar Surface Area (TPSA) 302.00 Ų
XlogP 0.50

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Ac-Aib-Aib-DL-Val-Aib-DL-xiIle-Aib-DL-Ala-DL-Ala-Aib-DL-Pro-ol

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 98.89% 98.95%
CHEMBL253 P34972 Cannabinoid CB2 receptor 98.00% 97.25%
CHEMBL3837 P07711 Cathepsin L 96.14% 96.61%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.81% 96.09%
CHEMBL4072 P07858 Cathepsin B 94.67% 93.67%
CHEMBL4588 P22894 Matrix metalloproteinase 8 94.00% 94.66%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 93.92% 98.33%
CHEMBL3359 P21462 Formyl peptide receptor 1 93.47% 93.56%
CHEMBL333 P08253 Matrix metalloproteinase-2 93.36% 96.31%
CHEMBL340 P08684 Cytochrome P450 3A4 92.87% 91.19%
CHEMBL4394 Q9NYA1 Sphingosine kinase 1 91.79% 96.03%
CHEMBL5966 P55899 IgG receptor FcRn large subunit p51 90.84% 90.93%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 90.81% 100.00%
CHEMBL2514 O95665 Neurotensin receptor 2 88.89% 100.00%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 88.52% 93.04%
CHEMBL1873 P00750 Tissue-type plasminogen activator 87.65% 93.33%
CHEMBL3137262 O60341 LSD1/CoREST complex 87.07% 97.09%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 86.98% 96.47%
CHEMBL218 P21554 Cannabinoid CB1 receptor 86.53% 96.61%
CHEMBL3437 Q16853 Amine oxidase, copper containing 86.25% 94.00%
CHEMBL2955 O95136 Sphingosine 1-phosphate receptor Edg-5 86.20% 92.86%
CHEMBL4801 P29466 Caspase-1 86.16% 96.85%
CHEMBL4073 P09237 Matrix metalloproteinase 7 86.11% 97.56%
CHEMBL2140 P48775 Tryptophan 2,3-dioxygenase 85.67% 98.46%
CHEMBL5203 P33316 dUTP pyrophosphatase 85.45% 99.18%
CHEMBL3430907 Q96GD4 Aurora kinase B/Inner centromere protein 85.35% 97.50%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 84.83% 96.38%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 84.65% 94.33%
CHEMBL4227 P25090 Lipoxin A4 receptor 84.45% 100.00%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 83.65% 100.00%
CHEMBL3145 P42338 PI3-kinase p110-beta subunit 83.44% 98.75%
CHEMBL3691 Q13822 Autotaxin 83.40% 96.39%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 82.88% 96.95%
CHEMBL4979 P13866 Sodium/glucose cotransporter 1 82.78% 98.24%
CHEMBL4018 P49146 Neuropeptide Y receptor type 2 82.36% 98.94%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 82.36% 97.14%
CHEMBL4618 P09960 Leukotriene A4 hydrolase 82.27% 97.86%
CHEMBL4005 P42336 PI3-kinase p110-alpha subunit 82.08% 97.47%
CHEMBL4361 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 81.94% 95.52%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 81.90% 96.90%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 81.04% 97.21%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 80.90% 93.03%
CHEMBL1075317 P61964 WD repeat-containing protein 5 80.46% 96.33%
CHEMBL3202 P48147 Prolyl endopeptidase 80.41% 90.65%
CHEMBL335 P18031 Protein-tyrosine phosphatase 1B 80.30% 95.17%
CHEMBL5608 Q16288 NT-3 growth factor receptor 80.28% 95.89%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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Cross-Links

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PubChem 56681245
LOTUS LTS0199119
wikiData Q104168548