Tmc-52C

Details

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Internal ID a85fbfeb-cbd5-40e4-9c83-5f0bcf499665
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Alpha amino acids and derivatives > Phenylalanine and derivatives
IUPAC Name 3-[[(2S)-1-[3-(4-aminobutylamino)propylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]oxirane-2-carboxylic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C20H30N4O5/c21-9-4-5-10-22-11-6-12-23-18(25)15(13-14-7-2-1-3-8-14)24-19(26)16-17(29-16)20(27)28/h1-3,7-8,15-17,22H,4-6,9-13,21H2,(H,23,25)(H,24,26)(H,27,28)/t15-,16?,17?/m0/s1
InChI Key LYAOVDVXUUARTK-GTPINHCMSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C20H30N4O5
Molecular Weight 406.50 g/mol
Exact Mass 406.22162007 g/mol
Topological Polar Surface Area (TPSA) 146.00 Ų
XlogP -2.40

Synonyms

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(2R*,3R*)-3-{[(2S)-1-({3-[(4-aminobutyl)amino]propyl}amino)-1-oxo-3-phenylpropan-2-yl]carbamoyl}oxirane-2-carboxylic acid
CHEBI:66240
Q27134783

2D Structure

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2D Structure of Tmc-52C

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 98.94% 98.95%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.25% 91.11%
CHEMBL3891 P07384 Calpain 1 96.07% 93.04%
CHEMBL1255126 O15151 Protein Mdm4 95.61% 90.20%
CHEMBL3060 Q9Y345 Glycine transporter 2 94.38% 99.17%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 93.78% 95.56%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 93.74% 96.09%
CHEMBL3492 P49721 Proteasome Macropain subunit 93.66% 90.24%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 92.26% 98.33%
CHEMBL4227 P25090 Lipoxin A4 receptor 91.27% 100.00%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 91.09% 95.50%
CHEMBL5701 Q9H2K8 Serine/threonine-protein kinase TAO3 89.93% 96.67%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 89.87% 95.00%
CHEMBL1907594 P30926 Neuronal acetylcholine receptor; alpha3/beta4 89.72% 97.23%
CHEMBL221 P23219 Cyclooxygenase-1 88.70% 90.17%
CHEMBL2514 O95665 Neurotensin receptor 2 88.07% 100.00%
CHEMBL2327 P21452 Neurokinin 2 receptor 87.72% 98.89%
CHEMBL5261 Q7L7X3 Serine/threonine-protein kinase TAO1 87.28% 89.33%
CHEMBL3401 O75469 Pregnane X receptor 86.86% 94.73%
CHEMBL5028 O14672 ADAM10 86.21% 97.50%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 83.51% 91.71%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 80.54% 97.14%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 80.31% 100.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 70678752
LOTUS LTS0090481
wikiData Q105278878