12,18-Di(butan-2-yl)-24-hydroxy-3,4,10,13,21,25-hexamethyl-26-pent-2-en-2-yl-6,15-di(propan-2-yl)-1,19-dioxa-4,7,10,13,16-pentazacyclohexacos-21-ene-2,5,8,11,14,17,20-heptone

Details

Top
Internal ID 509e2873-60b2-458b-9b9f-1e8beb82cff0
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name 12,18-di(butan-2-yl)-24-hydroxy-3,4,10,13,21,25-hexamethyl-26-pent-2-en-2-yl-6,15-di(propan-2-yl)-1,19-dioxa-4,7,10,13,16-pentazacyclohexacos-21-ene-2,5,8,11,14,17,20-heptone
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C44H75N5O10/c1-17-20-28(10)37-30(12)32(50)22-21-29(11)43(56)59-38(27(9)19-3)39(52)46-35(25(6)7)41(54)49(16)36(26(8)18-2)42(55)47(14)23-33(51)45-34(24(4)5)40(53)48(15)31(13)44(57)58-37/h20-21,24-27,30-32,34-38,50H,17-19,22-23H2,1-16H3,(H,45,51)(H,46,52)
InChI Key LRWWIPZJXHBJSP-UHFFFAOYSA-N
Popularity 0 references in papers

Physical and Chemical Properties

Top
Molecular Formula C44H75N5O10
Molecular Weight 834.10 g/mol
Exact Mass 833.55139361 g/mol
Topological Polar Surface Area (TPSA) 192.00 Ų
XlogP 7.00

Synonyms

Top
There are no found synonyms.

2D Structure

Top
2D Structure of 12,18-Di(butan-2-yl)-24-hydroxy-3,4,10,13,21,25-hexamethyl-26-pent-2-en-2-yl-6,15-di(propan-2-yl)-1,19-dioxa-4,7,10,13,16-pentazacyclohexacos-21-ene-2,5,8,11,14,17,20-heptone

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 97.94% 98.95%
CHEMBL253 P34972 Cannabinoid CB2 receptor 97.66% 97.25%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.68% 96.09%
CHEMBL3401 O75469 Pregnane X receptor 96.63% 94.73%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.13% 95.56%
CHEMBL5103 Q969S8 Histone deacetylase 10 94.23% 90.08%
CHEMBL1949 P62937 Cyclophilin A 93.19% 98.57%
CHEMBL3310 Q96DB2 Histone deacetylase 11 90.77% 88.56%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 89.78% 93.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 89.24% 97.09%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 88.95% 85.14%
CHEMBL255 P29275 Adenosine A2b receptor 88.04% 98.59%
CHEMBL1806 P11388 DNA topoisomerase II alpha 87.41% 89.00%
CHEMBL1937 Q92769 Histone deacetylase 2 86.78% 94.75%
CHEMBL226 P30542 Adenosine A1 receptor 85.39% 95.93%
CHEMBL3359 P21462 Formyl peptide receptor 1 83.49% 93.56%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 83.48% 94.45%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 83.35% 96.47%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 83.17% 91.11%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 82.16% 99.23%
CHEMBL4208 P20618 Proteasome component C5 82.00% 90.00%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 80.24% 90.71%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

Top
PubChem 73073389
LOTUS LTS0023872
wikiData Q104171263