Microginin GH787

Details

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Internal ID a1927f29-bdad-4325-aa1f-af68f7040d46
Taxonomy Organic acids and derivatives > Peptidomimetics > Hybrid peptides
IUPAC Name (2S)-2-[[(2S)-1-[(2S,3S)-2-[[(2S)-2-[[(2S,3R)-3-amino-10-chloro-2-hydroxydecanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]-methylamino]-3-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C40H58ClN5O9/c1-4-25(2)34(39(53)46-22-10-12-33(46)36(50)44-32(40(54)55)24-27-15-19-29(48)20-16-27)45(3)38(52)31(23-26-13-17-28(47)18-14-26)43-37(51)35(49)30(42)11-8-6-5-7-9-21-41/h13-20,25,30-35,47-49H,4-12,21-24,42H2,1-3H3,(H,43,51)(H,44,50)(H,54,55)/t25-,30+,31-,32-,33-,34-,35-/m0/s1
InChI Key XYGVUPXPWWMUAK-YGKFCERESA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C40H58ClN5O9
Molecular Weight 788.40 g/mol
Exact Mass 787.3923061 g/mol
Topological Polar Surface Area (TPSA) 223.00 Ų
XlogP 2.40

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Microginin GH787

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.84% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.22% 96.09%
CHEMBL2514 O95665 Neurotensin receptor 2 98.54% 100.00%
CHEMBL2107 P61073 C-X-C chemokine receptor type 4 98.53% 93.10%
CHEMBL3837 P07711 Cathepsin L 98.00% 96.61%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 96.73% 98.33%
CHEMBL3359 P21462 Formyl peptide receptor 1 95.58% 93.56%
CHEMBL3192 Q9BY41 Histone deacetylase 8 95.04% 93.99%
CHEMBL3060 Q9Y345 Glycine transporter 2 94.98% 99.17%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 94.19% 90.71%
CHEMBL4123 P30989 Neurotensin receptor 1 94.17% 96.67%
CHEMBL4227 P25090 Lipoxin A4 receptor 92.78% 100.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 92.78% 95.89%
CHEMBL4979 P13866 Sodium/glucose cotransporter 1 92.18% 98.24%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 91.81% 95.89%
CHEMBL4361 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 91.76% 95.52%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 91.20% 95.56%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 90.61% 94.45%
CHEMBL4198 P98170 Inhibitor of apoptosis protein 3 90.47% 97.79%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 90.28% 100.00%
CHEMBL5103 Q969S8 Histone deacetylase 10 89.99% 90.08%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 89.98% 100.00%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 89.70% 97.64%
CHEMBL335 P18031 Protein-tyrosine phosphatase 1B 89.47% 95.17%
CHEMBL340 P08684 Cytochrome P450 3A4 89.27% 91.19%
CHEMBL206 P03372 Estrogen receptor alpha 88.97% 97.64%
CHEMBL3137262 O60341 LSD1/CoREST complex 88.63% 97.09%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 88.27% 93.00%
CHEMBL1978 P11511 Cytochrome P450 19A1 87.25% 91.76%
CHEMBL236 P41143 Delta opioid receptor 86.93% 99.35%
CHEMBL1255126 O15151 Protein Mdm4 86.63% 90.20%
CHEMBL3892 Q99500 Sphingosine 1-phosphate receptor Edg-3 86.60% 97.29%
CHEMBL5043 Q6P179 Endoplasmic reticulum aminopeptidase 2 86.30% 91.81%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 84.59% 96.95%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 84.30% 97.14%
CHEMBL221 P23219 Cyclooxygenase-1 84.27% 90.17%
CHEMBL2955 O95136 Sphingosine 1-phosphate receptor Edg-5 83.72% 92.86%
CHEMBL4394 Q9NYA1 Sphingosine kinase 1 83.55% 96.03%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 83.13% 91.11%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 83.09% 94.33%
CHEMBL1907599 P05556 Integrin alpha-4/beta-1 82.73% 92.86%
CHEMBL1907594 P30926 Neuronal acetylcholine receptor; alpha3/beta4 82.59% 97.23%
CHEMBL2327 P21452 Neurokinin 2 receptor 82.44% 98.89%
CHEMBL5203 P33316 dUTP pyrophosphatase 82.22% 99.18%
CHEMBL3430907 Q96GD4 Aurora kinase B/Inner centromere protein 82.07% 97.50%
CHEMBL4208 P20618 Proteasome component C5 81.94% 90.00%
CHEMBL249 P25103 Neurokinin 1 receptor 81.59% 99.17%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 80.64% 95.00%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 80.31% 96.47%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 53361003
LOTUS LTS0128887
wikiData Q77489350