(2R)-5,7-dihydroxy-2-(7-hydroxy-2,2-dimethylchromen-6-yl)-8-(3-hydroxy-3-methylbutyl)-2,3-dihydrochromen-4-one

Details

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Internal ID 572ff01e-52f3-4589-8b6c-63a5189cf0e9
Taxonomy Phenylpropanoids and polyketides > Flavonoids > Flavans > 8-prenylated flavans > 8-prenylated flavanones
IUPAC Name (2R)-5,7-dihydroxy-2-(7-hydroxy-2,2-dimethylchromen-6-yl)-8-(3-hydroxy-3-methylbutyl)-2,3-dihydrochromen-4-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C25H28O7/c1-24(2,30)7-6-14-16(26)10-18(28)22-19(29)12-21(31-23(14)22)15-9-13-5-8-25(3,4)32-20(13)11-17(15)27/h5,8-11,21,26-28,30H,6-7,12H2,1-4H3/t21-/m1/s1
InChI Key YRFONVUVHGLFMJ-OAQYLSRUSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C25H28O7
Molecular Weight 440.50 g/mol
Exact Mass 440.18350323 g/mol
Topological Polar Surface Area (TPSA) 116.00 Ų
XlogP 3.90

Synonyms

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BDBM50114929

2D Structure

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2D Structure of (2R)-5,7-dihydroxy-2-(7-hydroxy-2,2-dimethylchromen-6-yl)-8-(3-hydroxy-3-methylbutyl)-2,3-dihydrochromen-4-one

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.98% 91.11%
CHEMBL2581 P07339 Cathepsin D 96.93% 98.95%
CHEMBL253 P34972 Cannabinoid CB2 receptor 95.91% 97.25%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 93.66% 96.09%
CHEMBL1806 P11388 DNA topoisomerase II alpha 93.08% 89.00%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 91.82% 94.45%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 91.75% 85.14%
CHEMBL1293249 Q13887 Kruppel-like factor 5 89.84% 86.33%
CHEMBL3004 P33527 Multidrug resistance-associated protein 1 88.33% 96.37%
CHEMBL3137262 O60341 LSD1/CoREST complex 88.15% 97.09%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 87.90% 96.77%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 85.20% 95.56%
CHEMBL215 P09917 Arachidonate 5-lipoxygenase 85.19% 92.68%
CHEMBL4208 P20618 Proteasome component C5 84.80% 90.00%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 84.33% 99.23%
CHEMBL4051 P13569 Cystic fibrosis transmembrane conductance regulator 83.54% 95.71%
CHEMBL218 P21554 Cannabinoid CB1 receptor 83.43% 96.61%
CHEMBL233 P35372 Mu opioid receptor 82.80% 97.93%
CHEMBL3401 O75469 Pregnane X receptor 82.58% 94.73%
CHEMBL2964 P36507 Dual specificity mitogen-activated protein kinase kinase 2 82.57% 80.00%
CHEMBL226 P30542 Adenosine A1 receptor 81.86% 95.93%
CHEMBL5469 Q14289 Protein tyrosine kinase 2 beta 81.34% 91.03%
CHEMBL5608 Q16288 NT-3 growth factor receptor 81.08% 95.89%
CHEMBL236 P41143 Delta opioid receptor 80.75% 99.35%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 80.45% 91.07%
CHEMBL1902 P62942 FK506-binding protein 1A 80.37% 97.05%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Maclura tricuspidata

Cross-Links

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PubChem 122187384
LOTUS LTS0230039
wikiData Q105352766