8,9-Dihydrolactimidomycin

Details

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Internal ID 30e4c5ed-b82c-44da-a33a-9cbefeb62a2f
Taxonomy Phenylpropanoids and polyketides > Macrolides and analogues
IUPAC Name 4-[(E,2R,5S)-2-hydroxy-5-methyl-7-[(2R,3S,6E,10E)-3-methyl-12-oxo-1-oxacyclododeca-6,10-dien-2-yl]-4-oxooct-6-enyl]piperidine-2,6-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C26H37NO6/c1-17-10-8-6-4-5-7-9-11-25(32)33-26(17)19(3)12-18(2)22(29)16-21(28)13-20-14-23(30)27-24(31)15-20/h4,6,9,11-12,17-18,20-21,26,28H,5,7-8,10,13-16H2,1-3H3,(H,27,30,31)/b6-4+,11-9+,19-12+/t17-,18-,21+,26+/m0/s1
InChI Key JMMMWKAJHBCSAV-XZBFPPINSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C26H37NO6
Molecular Weight 459.60 g/mol
Exact Mass 459.26208790 g/mol
Topological Polar Surface Area (TPSA) 110.00 Ų
XlogP 3.20

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of 8,9-Dihydrolactimidomycin

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.07% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 96.57% 94.45%
CHEMBL2581 P07339 Cathepsin D 96.29% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.11% 96.09%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 93.50% 85.14%
CHEMBL2553 Q15418 Ribosomal protein S6 kinase alpha 1 92.37% 85.11%
CHEMBL5103 Q969S8 Histone deacetylase 10 92.26% 90.08%
CHEMBL253 P34972 Cannabinoid CB2 receptor 92.01% 97.25%
CHEMBL1293267 Q9HC97 G-protein coupled receptor 35 91.44% 89.34%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 91.11% 94.80%
CHEMBL3137262 O60341 LSD1/CoREST complex 89.82% 97.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 89.59% 95.56%
CHEMBL3830 Q2M2I8 Adaptor-associated kinase 88.20% 83.10%
CHEMBL255 P29275 Adenosine A2b receptor 87.36% 98.59%
CHEMBL3310 Q96DB2 Histone deacetylase 11 87.28% 88.56%
CHEMBL1806 P11388 DNA topoisomerase II alpha 87.02% 89.00%
CHEMBL4040 P28482 MAP kinase ERK2 86.60% 83.82%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 86.41% 92.88%
CHEMBL1994 P08235 Mineralocorticoid receptor 85.16% 100.00%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 83.91% 95.89%
CHEMBL213 P08588 Beta-1 adrenergic receptor 83.30% 95.56%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 82.39% 96.47%
CHEMBL3359 P21462 Formyl peptide receptor 1 82.33% 93.56%
CHEMBL3060 Q9Y345 Glycine transporter 2 82.13% 99.17%
CHEMBL340 P08684 Cytochrome P450 3A4 81.43% 91.19%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 80.21% 91.07%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 101450768
LOTUS LTS0173522
wikiData Q77422863