8,5'-Diferulic acid

Details

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Internal ID 6ba60536-011b-4054-ae64-b88da99c12e5
Taxonomy Phenylpropanoids and polyketides > Stilbenes
IUPAC Name (E)-2-[5-[(E)-2-carboxyethenyl]-2-hydroxy-3-methoxyphenyl]-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
SMILES (Canonical) COC1=CC(=CC(=C1O)C(=CC2=CC(=C(C=C2)O)OC)C(=O)O)C=CC(=O)O
SMILES (Isomeric) COC1=CC(=CC(=C1O)/C(=C\C2=CC(=C(C=C2)O)OC)/C(=O)O)/C=C/C(=O)O
InChI InChI=1S/C20H18O8/c1-27-16-9-11(3-5-15(16)21)8-14(20(25)26)13-7-12(4-6-18(22)23)10-17(28-2)19(13)24/h3-10,21,24H,1-2H3,(H,22,23)(H,25,26)/b6-4+,14-8+
InChI Key DEPVSDIYICBTJE-SITOFEAGSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C20H18O8
Molecular Weight 386.40 g/mol
Exact Mass 386.10016753 g/mol
Topological Polar Surface Area (TPSA) 134.00 Ų
XlogP 2.70

Synonyms

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5-8'-Dehydrodiferulic acid
8,5'-DiFA
Ferulic acid 8-5-dehydrodimer
SCHEMBL20549053
CHEBI:88363
DTXSID201045390
Q15410237
(2E)-2-{5-[(E)-2-carboxyethenyl]-2-hydroxy-3-methoxyphenyl}-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
(E)-2-(5-((E)-2-Carboxyvinyl)-2-hydroxy-3-methoxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid
(E)-2-[5-[(E)-2-carboxyethenyl]-2-hydroxy-3-methoxyphenyl]-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

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2D Structure of 8,5'-Diferulic acid

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.36% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 96.39% 95.56%
CHEMBL1293249 Q13887 Kruppel-like factor 5 93.94% 86.33%
CHEMBL3194 P02766 Transthyretin 93.28% 90.71%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 90.94% 96.00%
CHEMBL1951 P21397 Monoamine oxidase A 90.61% 91.49%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 86.18% 96.09%
CHEMBL225 P28335 Serotonin 2c (5-HT2c) receptor 85.21% 89.62%
CHEMBL1806 P11388 DNA topoisomerase II alpha 82.96% 89.00%
CHEMBL4208 P20618 Proteasome component C5 82.47% 90.00%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 82.43% 95.50%
CHEMBL2535 P11166 Glucose transporter 81.44% 98.75%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 81.22% 99.15%
CHEMBL3060 Q9Y345 Glycine transporter 2 81.13% 99.17%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 80.30% 94.45%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 10385447
LOTUS LTS0138055
wikiData Q15410237