8-Hexanoylneosolaniol

Details

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Internal ID 337755f3-eae6-4032-9eaf-096ce3555c28
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Sesquiterpenoids > Trichothecenes
IUPAC Name [(1S,2R,4S,7R,9R,10R,11S)-11-acetyloxy-2-(acetyloxymethyl)-10-hydroxy-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-4-yl] hexanoate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C25H36O9/c1-6-7-8-9-19(28)33-17-11-24(12-30-15(3)26)18(10-14(17)2)34-22-20(29)21(32-16(4)27)23(24,5)25(22)13-31-25/h10,17-18,20-22,29H,6-9,11-13H2,1-5H3/t17-,18+,20+,21+,22+,23+,24+,25?/m0/s1
InChI Key NTQOBLPQKXJXCZ-BFAIXHJHSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C25H36O9
Molecular Weight 480.50 g/mol
Exact Mass 480.23593272 g/mol
Topological Polar Surface Area (TPSA) 121.00 Ų
XlogP 1.60

Synonyms

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[(1S,2R,4S,7R,9R,10R,11S)-11-Acetyloxy-2-(acetyloxymethyl)-10-hydroxy-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-4-yl] hexanoate
((1S,2R,4S,7R,9R,10R,11S)-11-acetyloxy-2-(acetyloxymethyl)-10-hydroxy-1,5-dimethylspiro(8-oxatricyclo(7.2.1.02,7)dodec-5-ene-12,2'-oxirane)-4-yl) hexanoate
RefChem:107116
118143-01-4
8-n-Hexanoylneosolaniol
SCHEMBL31570931
DTXSID20922614
CHEBI:175768
Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 4,15-diacetate 8-hexanoate, (3alpha,4beta,8alpha)-
4,15-Bis(acetyloxy)-3-hydroxy-12,13-epoxytrichothec-9-en-8-yl hexanoate
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

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2D Structure of 8-Hexanoylneosolaniol

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.76% 96.09%
CHEMBL253 P34972 Cannabinoid CB2 receptor 98.26% 97.25%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.20% 91.11%
CHEMBL2581 P07339 Cathepsin D 95.44% 98.95%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 93.86% 94.45%
CHEMBL230 P35354 Cyclooxygenase-2 93.68% 89.63%
CHEMBL3060 Q9Y345 Glycine transporter 2 93.22% 99.17%
CHEMBL5255 O00206 Toll-like receptor 4 92.38% 92.50%
CHEMBL3137262 O60341 LSD1/CoREST complex 90.52% 97.09%
CHEMBL2996 Q05655 Protein kinase C delta 90.47% 97.79%
CHEMBL3401 O75469 Pregnane X receptor 90.24% 94.73%
CHEMBL221 P23219 Cyclooxygenase-1 88.79% 90.17%
CHEMBL1293249 Q13887 Kruppel-like factor 5 88.71% 86.33%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 84.57% 94.33%
CHEMBL1293316 Q9HBX9 Relaxin receptor 1 84.38% 82.50%
CHEMBL4227 P25090 Lipoxin A4 receptor 83.97% 100.00%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 83.63% 100.00%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 83.23% 99.23%
CHEMBL1994 P08235 Mineralocorticoid receptor 82.92% 100.00%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 82.54% 82.69%
CHEMBL1806 P11388 DNA topoisomerase II alpha 82.39% 89.00%
CHEMBL299 P17252 Protein kinase C alpha 82.28% 98.03%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 81.64% 94.80%
CHEMBL1907602 P06493 Cyclin-dependent kinase 1/cyclin B1 80.95% 91.24%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 80.41% 96.90%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 3081149
LOTUS LTS0226922
wikiData Q82896236