(7R,9R,10S)-Aklavinone

Details

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Internal ID 14e253a6-f6c1-414a-a2ae-696a9aa5e985
Taxonomy Benzenoids > Naphthacenes > Tetracenequinones
IUPAC Name methyl (1S,2R,4R)-2-ethyl-2,4,5,7-tetrahydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C22H20O8/c1-3-22(29)8-13(24)15-10(17(22)21(28)30-2)7-11-16(20(15)27)19(26)14-9(18(11)25)5-4-6-12(14)23/h4-7,13,17,23-24,27,29H,3,8H2,1-2H3/t13-,17-,22-/m1/s1
InChI Key RACGRCLGVYXIAO-NYFKNOIKSA-N
Popularity 4 references in papers

Physical and Chemical Properties

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Molecular Formula C22H20O8
Molecular Weight 412.40 g/mol
Exact Mass 412.11581759 g/mol
Topological Polar Surface Area (TPSA) 141.00 Ų
XlogP 2.50

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of (7R,9R,10S)-Aklavinone

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.16% 98.95%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 99.12% 96.38%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.11% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.59% 96.09%
CHEMBL1806 P11388 DNA topoisomerase II alpha 93.37% 89.00%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 91.81% 85.14%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 91.69% 95.56%
CHEMBL226 P30542 Adenosine A1 receptor 89.16% 95.93%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 88.43% 99.23%
CHEMBL2535 P11166 Glucose transporter 87.89% 98.75%
CHEMBL5608 Q16288 NT-3 growth factor receptor 87.57% 95.89%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 87.05% 82.69%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 86.25% 93.03%
CHEMBL1293249 Q13887 Kruppel-like factor 5 84.41% 86.33%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 83.37% 94.00%
CHEMBL1951 P21397 Monoamine oxidase A 83.24% 91.49%
CHEMBL340 P08684 Cytochrome P450 3A4 82.18% 91.19%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 81.96% 94.45%
CHEMBL4208 P20618 Proteasome component C5 81.76% 90.00%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 81.75% 90.71%
CHEMBL2378 P30307 Dual specificity phosphatase Cdc25C 81.33% 96.67%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 80.87% 91.07%
CHEMBL1907602 P06493 Cyclin-dependent kinase 1/cyclin B1 80.09% 91.24%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

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PubChem 139587812
LOTUS LTS0212020
wikiData Q77624608