7beta-Hydroxycholest-4-en-3-one

Details

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Internal ID b80de38f-19d0-470e-8dd1-3bdc173f2cf4
Taxonomy Lipids and lipid-like molecules > Steroids and steroid derivatives > Cholestane steroids > Cholesterols and derivatives
IUPAC Name (7S,8S,9S,10R,13R,14S,17R)-7-hydroxy-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C27H44O2/c1-17(2)7-6-8-18(3)21-9-10-22-25-23(12-14-27(21,22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h15,17-18,21-25,29H,6-14,16H2,1-5H3/t18-,21-,22+,23+,24+,25+,26+,27-/m1/s1
InChI Key IOIZWEJGGCZDOL-BXLWXSRCSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C27H44O2
Molecular Weight 400.60 g/mol
Exact Mass 400.334130642 g/mol
Topological Polar Surface Area (TPSA) 37.30 Ų
XlogP 7.30

Synonyms

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7beta-Hydroxycholest-4-en-3-one
7beta-Hydroxy-4-cholesten-3-one
7b-Hydroxy-4-cholesten-3-one
(7S,8S,9S,10R,13R,14S,17R)-7-hydroxy-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
4-CHOLESTEN-7-BETA-OL-3-ONE
4-Cholesten-7beta-ol-3-one
Cholest-4-en-3-one, 7-hydroxy-, (7ss)-; Cholest-4-en-3-one, 7ss-hydroxy- (8CI); (7ss)-7-Hydroxycholest-4-en-3-one; ?4-7ss-Hydroxycholestenone; 7ss-Hydroxy-4-cholesten-3-one; 7ss-Hydroxycholest-4-en-3-one
SCHEMBL735215
DTXSID60415292
7 beta -Hydroxy-4-cholesten-3-one
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

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2D Structure of 7beta-Hydroxycholest-4-en-3-one

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 98.08% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.06% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.14% 91.11%
CHEMBL253 P34972 Cannabinoid CB2 receptor 96.05% 97.25%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 95.47% 90.71%
CHEMBL1994 P08235 Mineralocorticoid receptor 95.43% 100.00%
CHEMBL226 P30542 Adenosine A1 receptor 95.38% 95.93%
CHEMBL1871 P10275 Androgen Receptor 93.78% 96.43%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 91.96% 94.45%
CHEMBL2179 P04062 Beta-glucocerebrosidase 91.68% 85.31%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 90.81% 95.89%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 89.29% 95.56%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 88.78% 85.14%
CHEMBL5608 Q16288 NT-3 growth factor receptor 86.48% 95.89%
CHEMBL221 P23219 Cyclooxygenase-1 85.34% 90.17%
CHEMBL237 P41145 Kappa opioid receptor 85.17% 98.10%
CHEMBL3137262 O60341 LSD1/CoREST complex 84.82% 97.09%
CHEMBL1293249 Q13887 Kruppel-like factor 5 83.19% 86.33%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 83.03% 82.69%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 82.66% 93.04%
CHEMBL5103 Q969S8 Histone deacetylase 10 80.55% 90.08%
CHEMBL1902 P62942 FK506-binding protein 1A 80.41% 97.05%
CHEMBL4227 P25090 Lipoxin A4 receptor 80.33% 100.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 5284280
LOTUS LTS0077030
wikiData Q82224221