(2-amino-4-(4-methoxyphenyl)butanoic acid)-AM toxin I

Details

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Internal ID 3e4c1b3f-224c-4ce2-aca3-439d8c4122b8
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name 9-[2-(4-methoxyphenyl)ethyl]-3-methyl-6-methylidene-12-propan-2-yl-1-oxa-4,7,10-triazacyclododecane-2,5,8,11-tetrone
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C22H29N3O6/c1-12(2)18-21(28)25-17(11-8-15-6-9-16(30-5)10-7-15)20(27)23-13(3)19(26)24-14(4)22(29)31-18/h6-7,9-10,12,14,17-18H,3,8,11H2,1-2,4-5H3,(H,23,27)(H,24,26)(H,25,28)
InChI Key YSONUVGWOCXRPA-UHFFFAOYSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C22H29N3O6
Molecular Weight 431.50 g/mol
Exact Mass 431.20563565 g/mol
Topological Polar Surface Area (TPSA) 123.00 Ų
XlogP 2.70

Synonyms

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(L-Amb3)-AM toxin I
(2-Amino-4-(4-methoxyphenyl)butanoic acid)-AM toxin I
87105-09-7
(L-2-Amino-4-(p-methoxxyphenyl)butanoic acid)-AM toxin I
AM Toxin I, (2-amino-4-(4-methoxyphenyl)butanoic acid)-
RefChem:68563
9-(2-(4-methoxyphenyl)ethyl)-3-methyl-6-methylidene-12-propan-2-yl-1-oxa-4,7,10-triazacyclododecane-2,5,8,11-tetrone
L-Alanine, N-(2-hydroxy-3-methyl-1-oxobutyl)-gamma-(4-methoxyphenyl)-L-alpha-aminobutyryl-2,3-didehydroalanyl-, (S)-
DTXSID801007340
5,8,11-Trihydroxy-9-[2-(4-methoxyphenyl)ethyl]-3-methyl-6-methylidene-12-(propan-2-yl)-1-oxa-4,7,10-triazacyclododeca-4,7,10-trien-2-one

2D Structure

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2D Structure of (2-amino-4-(4-methoxyphenyl)butanoic acid)-AM toxin I

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL253 P34972 Cannabinoid CB2 receptor 98.95% 97.25%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.03% 96.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 97.00% 94.45%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.88% 91.11%
CHEMBL1907 P15144 Aminopeptidase N 92.59% 93.31%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 91.95% 95.56%
CHEMBL2581 P07339 Cathepsin D 90.71% 98.95%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 89.29% 94.00%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 88.58% 95.50%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 86.59% 85.14%
CHEMBL3137262 O60341 LSD1/CoREST complex 85.90% 97.09%
CHEMBL5608 Q16288 NT-3 growth factor receptor 85.68% 95.89%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 83.29% 92.88%
CHEMBL3437 Q16853 Amine oxidase, copper containing 82.99% 94.00%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 82.68% 94.80%
CHEMBL1949 P62937 Cyclophilin A 82.23% 98.57%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 82.11% 97.14%
CHEMBL5957 P21589 5'-nucleotidase 81.73% 97.78%
CHEMBL3401 O75469 Pregnane X receptor 80.88% 94.73%
CHEMBL255 P29275 Adenosine A2b receptor 80.81% 98.59%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 174610
LOTUS LTS0049298
wikiData Q83003314