7-Hydroxy-beta-carboline-1-propionic acid

Details

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Internal ID e01ae5e3-ec60-48e9-b9f1-15ba42c45f29
Taxonomy Alkaloids and derivatives > Harmala alkaloids
IUPAC Name 3-(7-oxo-2,9-dihydropyrido[3,4-b]indol-1-yl)propanoic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C14H12N2O3/c17-8-1-2-9-10-5-6-15-11(3-4-13(18)19)14(10)16-12(9)7-8/h1-2,5-7,15-16H,3-4H2,(H,18,19)
InChI Key MBOPWGSKAKJDIH-UHFFFAOYSA-N
Popularity 5 references in papers

Physical and Chemical Properties

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Molecular Formula C14H12N2O3
Molecular Weight 256.26 g/mol
Exact Mass 256.08479225 g/mol
Topological Polar Surface Area (TPSA) 78.40 Ų
XlogP 0.10

Synonyms

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215934-15-9
3-(7-oxo-2,9-dihydropyrido[3,4-b]indol-1-yl)propanoic acid
CHEMBL5219042
AKOS040735330
FS-7582
3-(7-hydroxy-9h-beta-carboline-1-yl)propanoic acid

2D Structure

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2D Structure of 7-Hydroxy-beta-carboline-1-propionic acid

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4040 P28482 MAP kinase ERK2 98.33% 83.82%
CHEMBL2581 P07339 Cathepsin D 96.83% 98.95%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 95.97% 94.45%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.64% 91.11%
CHEMBL255 P29275 Adenosine A2b receptor 92.36% 98.59%
CHEMBL1781 P11387 DNA topoisomerase I 91.39% 97.00%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 90.39% 91.71%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 90.10% 95.56%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 88.11% 96.09%
CHEMBL1951 P21397 Monoamine oxidase A 87.37% 91.49%
CHEMBL213 P08588 Beta-1 adrenergic receptor 85.41% 95.56%
CHEMBL4016 P42262 Glutamate receptor ionotropic, AMPA 2 83.07% 86.92%
CHEMBL3060 Q9Y345 Glycine transporter 2 81.97% 99.17%
CHEMBL1806 P11388 DNA topoisomerase II alpha 81.70% 89.00%
CHEMBL1907 P15144 Aminopeptidase N 81.53% 93.31%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 10868897
LOTUS LTS0107629
wikiData Q77572159