7 alpha,12alpha-Dihydroxy-3-ketocholanic acid

Details

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Internal ID 227c8c69-9c4b-42a3-ae28-1a19e098fe78
Taxonomy Lipids and lipid-like molecules > Steroids and steroid derivatives > Bile acids, alcohols and derivatives > Hydroxy bile acids, alcohols and derivatives > Dihydroxy bile acids, alcohols and derivatives
IUPAC Name (4R)-4-[(7R,10S,12S,13R)-7,12-dihydroxy-10,13-dimethyl-3-oxo-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C24H38O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-14,16-20,22,26-27H,4-12H2,1-3H3,(H,28,29)/t13-,14?,16?,17?,18?,19-,20+,22?,23+,24-/m1/s1
InChI Key OEKUSRBIIZNLHZ-QHLUWSNTSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C24H38O5
Molecular Weight 406.60 g/mol
Exact Mass 406.27192431 g/mol
Topological Polar Surface Area (TPSA) 94.80 Ų
XlogP 3.20

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of 7 alpha,12alpha-Dihydroxy-3-ketocholanic acid

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.99% 96.09%
CHEMBL2581 P07339 Cathepsin D 97.53% 98.95%
CHEMBL253 P34972 Cannabinoid CB2 receptor 96.03% 97.25%
CHEMBL221 P23219 Cyclooxygenase-1 94.82% 90.17%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 93.45% 91.11%
CHEMBL3137262 O60341 LSD1/CoREST complex 92.44% 97.09%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 89.53% 85.14%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 89.45% 95.89%
CHEMBL2179 P04062 Beta-glucocerebrosidase 89.41% 85.31%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 88.31% 94.45%
CHEMBL340 P08684 Cytochrome P450 3A4 88.11% 91.19%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 88.01% 90.71%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 87.09% 93.00%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 86.66% 95.56%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 84.80% 93.04%
CHEMBL220 P22303 Acetylcholinesterase 84.57% 94.45%
CHEMBL1994 P08235 Mineralocorticoid receptor 84.34% 100.00%
CHEMBL2035 P08912 Muscarinic acetylcholine receptor M5 84.18% 94.62%
CHEMBL3359 P21462 Formyl peptide receptor 1 83.66% 93.56%
CHEMBL4227 P25090 Lipoxin A4 receptor 82.79% 100.00%
CHEMBL237 P41145 Kappa opioid receptor 82.32% 98.10%
CHEMBL2553 Q15418 Ribosomal protein S6 kinase alpha 1 82.00% 85.11%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 81.38% 99.23%
CHEMBL238 Q01959 Dopamine transporter 80.90% 95.88%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139588606
LOTUS LTS0192426
wikiData Q105190343