Guyonianin F

Details

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Internal ID 1938a478-46c2-4852-adb8-897751361f56
Taxonomy Phenylpropanoids and polyketides > Macrolides and analogues
IUPAC Name [(1R,2S,3S,4S,6R,8S,9S,10R,11S,16R,17R,19S,20R)-2,8,9,10,17-pentaacetyloxy-1,11-dihydroxy-3,7,7,17-tetramethyl-14-oxo-5,15-dioxatetracyclo[9.7.2.04,6.016,19]icosan-20-yl] benzoate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C39H50O17/c1-18-27-32(54-27)36(7,8)33(51-21(4)42)28(49-19(2)40)34(52-22(5)43)38(47)16-15-25(45)53-30-26(31(38)55-35(46)24-13-11-10-12-14-24)39(48,29(18)50-20(3)41)17-37(30,9)56-23(6)44/h10-14,18,26-34,47-48H,15-17H2,1-9H3/t18-,26+,27-,28-,29-,30+,31+,32-,33+,34+,37+,38-,39+/m0/s1
InChI Key AYEWXCGYVJFQDW-FQZPHRHVSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C39H50O17
Molecular Weight 790.80 g/mol
Exact Mass 790.30480012 g/mol
Topological Polar Surface Area (TPSA) 237.00 Ų
XlogP 2.10

Synonyms

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RefChem:922618
((1R,2S,3S,4S,6R,8S,9S,10R,11S,16R,17R,19S,20R)-2,8,9,10,17-pentaacetyloxy-1,11-dihydroxy-3,7,7,17-tetramethyl-14-oxo-5,15-dioxatetracyclo(9.7.2.04,6.016,19)icosan-20-yl) benzoate

2D Structure

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2D Structure of Guyonianin F

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL1293249 Q13887 Kruppel-like factor 5 97.35% 86.33%
CHEMBL2581 P07339 Cathepsin D 96.52% 98.95%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 93.86% 91.11%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 93.49% 99.23%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 92.21% 96.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 89.32% 95.56%
CHEMBL221 P23219 Cyclooxygenase-1 88.36% 90.17%
CHEMBL5028 O14672 ADAM10 87.15% 97.50%
CHEMBL340 P08684 Cytochrome P450 3A4 85.80% 91.19%
CHEMBL3475 P05121 Plasminogen activator inhibitor-1 85.26% 83.00%
CHEMBL2996 Q05655 Protein kinase C delta 83.61% 97.79%
CHEMBL1806 P11388 DNA topoisomerase II alpha 82.84% 89.00%
CHEMBL204 P00734 Thrombin 82.57% 96.01%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 82.15% 91.07%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 81.62% 95.50%
CHEMBL1821 P08173 Muscarinic acetylcholine receptor M4 81.57% 94.08%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 81.35% 97.14%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 81.34% 82.69%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Euphorbia guyoniana

Cross-Links

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PubChem 101499040
LOTUS LTS0125622
wikiData Q104921039