6,7-Methylenedioxy-2-(6-acetyl-2,3-methylene-dioxybenzyl)-1(2h)-isoquinolinone

Details

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Internal ID 9d42bcc3-881a-4419-9a4a-a672f84176df
Taxonomy Organoheterocyclic compounds > Isoquinolines and derivatives > Isoquinolones and derivatives
IUPAC Name 6-[(5-acetyl-1,3-benzodioxol-4-yl)methyl]-[1,3]dioxolo[4,5-g]isoquinolin-5-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C20H15NO6/c1-11(22)13-2-3-16-19(27-10-24-16)15(13)8-21-5-4-12-6-17-18(26-9-25-17)7-14(12)20(21)23/h2-7H,8-10H2,1H3
InChI Key OYCDIRUGACCROL-UHFFFAOYSA-N
Popularity 5 references in papers

Physical and Chemical Properties

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Molecular Formula C20H15NO6
Molecular Weight 365.30 g/mol
Exact Mass 365.08993720 g/mol
Topological Polar Surface Area (TPSA) 74.30 Ų
XlogP 2.30

Synonyms

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6,7-methylenedioxy-2-(6-acetyl-2,3-methylene-dioxybenzyl)-1(2h)-isoquinolinone

2D Structure

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2D Structure of 6,7-Methylenedioxy-2-(6-acetyl-2,3-methylene-dioxybenzyl)-1(2h)-isoquinolinone

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 95.86% 96.77%
CHEMBL240 Q12809 HERG 95.44% 89.76%
CHEMBL2581 P07339 Cathepsin D 94.40% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 93.80% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 93.79% 91.11%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 92.56% 93.40%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 92.51% 85.14%
CHEMBL1293249 Q13887 Kruppel-like factor 5 89.35% 86.33%
CHEMBL3864 Q06124 Protein-tyrosine phosphatase 2C 89.22% 94.42%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 89.17% 94.45%
CHEMBL2039 P27338 Monoamine oxidase B 88.98% 92.51%
CHEMBL1806 P11388 DNA topoisomerase II alpha 86.85% 89.00%
CHEMBL3401 O75469 Pregnane X receptor 86.43% 94.73%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 85.00% 92.62%
CHEMBL4208 P20618 Proteasome component C5 83.61% 90.00%
CHEMBL2107 P61073 C-X-C chemokine receptor type 4 82.85% 93.10%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 82.77% 94.00%
CHEMBL2096618 P11274 Bcr/Abl fusion protein 82.55% 85.83%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 81.47% 95.56%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 80.87% 99.23%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Corydalis bungeana

Cross-Links

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PubChem 12997611
LOTUS LTS0064827
wikiData Q105203110