6-Hydroxy-L-tryptophan

Details

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Internal ID 7b09330b-62c5-4262-bce6-86925fd56a59
Taxonomy Organoheterocyclic compounds > Indoles and derivatives > Indolyl carboxylic acids and derivatives
IUPAC Name (2S)-2-amino-3-(6-hydroxy-1H-indol-3-yl)propanoic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C11H12N2O3/c12-9(11(15)16)3-6-5-13-10-4-7(14)1-2-8(6)10/h1-2,4-5,9,13-14H,3,12H2,(H,15,16)/t9-/m0/s1
InChI Key NXANGIZFHQQBCC-VIFPVBQESA-N
Popularity 18 references in papers

Physical and Chemical Properties

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Molecular Formula C11H12N2O3
Molecular Weight 220.22 g/mol
Exact Mass 220.08479225 g/mol
Topological Polar Surface Area (TPSA) 99.30 Ų
XlogP -1.20

Synonyms

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(S)-2-Amino-3-(6-hydroxy-1H-indol-3-yl)propanoic acid
6-HYDROXY-L-TRYPTOPHAN
6-hydroxytryptophan
(2S)-2-amino-3-(6-hydroxy-1H-indol-3-yl)propanoic acid
Tryptophan, 6-hydroxy-
SCHEMBL179963
(S)-2-Amino-3-(6-hydroxy-1H-indol-3-yl)propanoicacid
DTXSID60678820
MFCD19105439
CS-W000483
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

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2D Structure of 6-Hydroxy-L-tryptophan

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.23% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.74% 96.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 94.85% 94.45%
CHEMBL4040 P28482 MAP kinase ERK2 94.17% 83.82%
CHEMBL225 P28335 Serotonin 2c (5-HT2c) receptor 94.07% 89.62%
CHEMBL2581 P07339 Cathepsin D 92.00% 98.95%
CHEMBL1255126 O15151 Protein Mdm4 91.52% 90.20%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 90.81% 99.15%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 90.69% 95.56%
CHEMBL213 P08588 Beta-1 adrenergic receptor 88.56% 95.56%
CHEMBL3060 Q9Y345 Glycine transporter 2 87.50% 99.17%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 86.80% 96.95%
CHEMBL2035 P08912 Muscarinic acetylcholine receptor M5 85.85% 94.62%
CHEMBL2535 P11166 Glucose transporter 84.16% 98.75%
CHEMBL3830 Q2M2I8 Adaptor-associated kinase 83.93% 83.10%
CHEMBL3194 P02766 Transthyretin 83.83% 90.71%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 83.03% 91.71%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 82.02% 97.21%
CHEMBL4101 P17612 cAMP-dependent protein kinase alpha-catalytic subunit 80.67% 82.86%
CHEMBL1907594 P30926 Neuronal acetylcholine receptor; alpha3/beta4 80.24% 97.23%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 49867758
LOTUS LTS0058079
wikiData Q27466719