PM-53

Details

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Internal ID ca969077-04ce-485e-b566-137ecdd573f4
Taxonomy Organoheterocyclic compounds > Indoles and derivatives > Indoles
IUPAC Name 2-(1H-indol-3-yl)-3,6-dimethoxy-5-[5-[(1E)-3-methylbuta-1,3-dienyl]-1H-indol-3-yl]cyclohexa-2,5-diene-1,4-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C29H24N2O4/c1-16(2)9-10-17-11-12-23-19(13-17)21(15-31-23)25-27(33)28(34-3)24(26(32)29(25)35-4)20-14-30-22-8-6-5-7-18(20)22/h5-15,30-31H,1H2,2-4H3/b10-9+
InChI Key CTZVPYADWNUQLM-MDZDMXLPSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C29H24N2O4
Molecular Weight 464.50 g/mol
Exact Mass 464.17360725 g/mol
Topological Polar Surface Area (TPSA) 84.20 Ų
XlogP 6.00

Synonyms

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198992-52-8
2-(1H-Indol-3-yl)-3,6-dimethoxy-5-(5-((1E)-3-methylbuta-1,3-dienyl)-1H-indol-3-yl)cyclohexa-2,5-diene-1,4-dione

2D Structure

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2D Structure of PM-53

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.29% 91.11%
CHEMBL1951 P21397 Monoamine oxidase A 99.24% 91.49%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 97.78% 95.56%
CHEMBL2581 P07339 Cathepsin D 95.93% 98.95%
CHEMBL1806 P11388 DNA topoisomerase II alpha 95.12% 89.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 91.95% 86.33%
CHEMBL2002 P12268 Inosine-5'-monophosphate dehydrogenase 2 90.39% 98.21%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 90.07% 96.00%
CHEMBL2708 Q16584 Mitogen-activated protein kinase kinase kinase 11 89.42% 81.14%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 87.97% 85.14%
CHEMBL1937 Q92769 Histone deacetylase 2 87.79% 94.75%
CHEMBL2535 P11166 Glucose transporter 87.77% 98.75%
CHEMBL3524 P56524 Histone deacetylase 4 84.26% 92.97%
CHEMBL2095172 P14867 GABA-A receptor; alpha-1/beta-2/gamma-2 83.65% 92.67%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 83.12% 91.71%
CHEMBL1868 P17948 Vascular endothelial growth factor receptor 1 81.71% 96.47%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 81.03% 94.45%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 80.69% 96.09%
CHEMBL4225 P49760 Dual specificity protein kinase CLK2 80.36% 80.96%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Baccharis scandens
Brickellia veronicaefolia

Cross-Links

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PubChem 6442233
LOTUS LTS0083490
wikiData Q105191482