(8,8'-Bi-1H-naphtho(2,3-c)pyran)-3,3'-diacetic acid, 3,3',4,4'-tetrahydro-9,9',10,10'-tetrahydroxy-7,7'-dimethoxy-1,1'-dioxo-, dimethyl ester

Details

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Internal ID 9fc0877d-54ba-4bda-bc6a-373d103481d0
Taxonomy Phenylpropanoids and polyketides > Tetracyclines
IUPAC Name 3',4',8',9',12',14'-hexahydroxy-16'-methoxy-1,5,5-trimethyl-6',10'-dioxospiro[cyclohexene-6,18'-pentacyclo[11.6.1.02,11.04,9.017,20]icosa-1(20),2(11),7,12,14,16-hexaene]-7'-carboxamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C30H31NO10/c1-11-6-5-7-27(2,3)28(11)9-12-16-18(13(32)8-15(41-4)21(16)28)22(34)20-17(12)23(35)29(39)10-14(33)19(26(31)38)24(36)30(29,40)25(20)37/h6,8,23,32,34-36,39-40H,5,7,9-10H2,1-4H3,(H2,31,38)
InChI Key FNSQKFOXORBCCC-UHFFFAOYSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C30H31NO10
Molecular Weight 565.60 g/mol
Exact Mass 565.19479619 g/mol
Topological Polar Surface Area (TPSA) 208.00 Ų
XlogP 2.30

Synonyms

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NSC159628
SCHEMBL13024388
SUWQGLGDFGHZNH-UHFFFAOYSA-N
Spiro[2-cyclohexene-1,2'(1'H)-cyclopenta[de]naphthacene]-9'-carboxamide, 7',7'a,8',11',11'a,12'-hexahydro-5',6',7'a,10',11'a,12'-hexahydroxy-3'-methoxy-2,6,6-trimethyl-7',8'-dioxo-, (2'.alpha.,7'a.beta.,11'a.beta.,12'.beta.)-(-)-
HY-129208
CS-0104456
(8,8'-Bi-1H-naphtho(2,3-c)pyran)-3,3'-diacetic acid, 3,3',4,4'-tetrahydro-9,9',10,10'-tetrahydroxy-7,7'-dimethoxy-1,1'-dioxo-, dimethyl ester

2D Structure

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2D Structure of (8,8'-Bi-1H-naphtho(2,3-c)pyran)-3,3'-diacetic acid, 3,3',4,4'-tetrahydro-9,9',10,10'-tetrahydroxy-7,7'-dimethoxy-1,1'-dioxo-, dimethyl ester

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.48% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.49% 96.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 96.63% 94.45%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 96.51% 95.56%
CHEMBL1937 Q92769 Histone deacetylase 2 94.47% 94.75%
CHEMBL241 Q14432 Phosphodiesterase 3A 93.66% 92.94%
CHEMBL2041 P07949 Tyrosine-protein kinase receptor RET 93.13% 91.79%
CHEMBL1806 P11388 DNA topoisomerase II alpha 91.31% 89.00%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 90.92% 94.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 90.72% 95.89%
CHEMBL2581 P07339 Cathepsin D 90.31% 98.95%
CHEMBL1293249 Q13887 Kruppel-like factor 5 89.95% 86.33%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 89.29% 91.07%
CHEMBL3137262 O60341 LSD1/CoREST complex 88.45% 97.09%
CHEMBL3192 Q9BY41 Histone deacetylase 8 88.43% 93.99%
CHEMBL3864 Q06124 Protein-tyrosine phosphatase 2C 88.14% 94.42%
CHEMBL3474 P14555 Phospholipase A2 group IIA 87.69% 94.05%
CHEMBL2535 P11166 Glucose transporter 86.94% 98.75%
CHEMBL340 P08684 Cytochrome P450 3A4 84.97% 91.19%
CHEMBL4829 O00763 Acetyl-CoA carboxylase 2 84.79% 98.00%
CHEMBL5469 Q14289 Protein tyrosine kinase 2 beta 84.69% 91.03%
CHEMBL253 P34972 Cannabinoid CB2 receptor 83.00% 97.25%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 82.59% 99.23%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 82.32% 99.15%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 81.68% 85.14%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 81.62% 93.03%
CHEMBL2964 P36507 Dual specificity mitogen-activated protein kinase kinase 2 81.61% 80.00%
CHEMBL2056 P21728 Dopamine D1 receptor 81.36% 91.00%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 81.07% 93.04%
CHEMBL4208 P20618 Proteasome component C5 80.73% 90.00%
CHEMBL1994 P08235 Mineralocorticoid receptor 80.47% 100.00%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 80.26% 96.21%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 80.17% 90.71%
CHEMBL5028 O14672 ADAM10 80.00% 97.50%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 54679209
LOTUS LTS0059633
wikiData Q104166574