5alpha(H),17alpha(H)-(20R)-3beta-ACETOXYCHOLEST-8(14)-ENE

Details

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Internal ID 9e1205d2-f1a5-4bf1-9bcc-ef0f8f40e69a
Taxonomy Lipids and lipid-like molecules > Steroids and steroid derivatives > Cholestane steroids
IUPAC Name [(3S,5S,9R,10S,13R,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate
SMILES (Canonical) CC(C)CCCC(C)C1CCC2=C3CCC4CC(CCC4(C3CCC12C)C)OC(=O)C
SMILES (Isomeric) C[C@H](CCCC(C)C)[C@H]1CCC2=C3CC[C@H]4C[C@H](CC[C@@]4([C@H]3CC[C@]12C)C)OC(=O)C
InChI InChI=1S/C29H48O2/c1-19(2)8-7-9-20(3)25-12-13-26-24-11-10-22-18-23(31-21(4)30)14-16-28(22,5)27(24)15-17-29(25,26)6/h19-20,22-23,25,27H,7-18H2,1-6H3/t20-,22+,23+,25-,27+,28+,29-/m1/s1
InChI Key VNJBUCCXHRSVLO-ZSKZXBCESA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C29H48O2
Molecular Weight 428.70 g/mol
Exact Mass 428.365430770 g/mol
Topological Polar Surface Area (TPSA) 26.30 Ų
XlogP 8.60

Synonyms

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[(3S,5S,9R,10S,13R,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate
6562-21-6
SCHEMBL9164298

2D Structure

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2D Structure of 5alpha(H),17alpha(H)-(20R)-3beta-ACETOXYCHOLEST-8(14)-ENE

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.84% 96.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 97.81% 94.45%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.69% 91.11%
CHEMBL253 P34972 Cannabinoid CB2 receptor 95.88% 97.25%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 91.83% 95.89%
CHEMBL3137262 O60341 LSD1/CoREST complex 91.67% 97.09%
CHEMBL2581 P07339 Cathepsin D 91.62% 98.95%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 91.15% 82.69%
CHEMBL237 P41145 Kappa opioid receptor 89.81% 98.10%
CHEMBL4227 P25090 Lipoxin A4 receptor 87.29% 100.00%
CHEMBL3359 P21462 Formyl peptide receptor 1 87.20% 93.56%
CHEMBL340 P08684 Cytochrome P450 3A4 87.03% 91.19%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 86.50% 96.38%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 85.83% 92.62%
CHEMBL1994 P08235 Mineralocorticoid receptor 85.71% 100.00%
CHEMBL3975 P09467 Fructose-1,6-bisphosphatase 85.55% 92.95%
CHEMBL2782 P35610 Acyl coenzyme A:cholesterol acyltransferase 1 85.28% 91.65%
CHEMBL3267 P48736 PI3-kinase p110-gamma subunit 84.33% 95.71%
CHEMBL5608 Q16288 NT-3 growth factor receptor 82.61% 95.89%
CHEMBL4681 P42330 Aldo-keto-reductase family 1 member C3 82.28% 89.05%
CHEMBL2413 P32246 C-C chemokine receptor type 1 82.03% 89.50%
CHEMBL3060 Q9Y345 Glycine transporter 2 81.88% 99.17%
CHEMBL3430907 Q96GD4 Aurora kinase B/Inner centromere protein 81.82% 97.50%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 81.43% 98.33%
CHEMBL2514 O95665 Neurotensin receptor 2 81.35% 100.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Dioscorea polystachya

Cross-Links

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PubChem 14861196
LOTUS LTS0127776
wikiData Q105289669