5alpha,8alpha-Epidioxycholest-6-en-3beta-ol

Details

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Internal ID 7999cabd-643c-4520-9601-d9c2645e1f6c
Taxonomy Lipids and lipid-like molecules > Steroids and steroid derivatives
IUPAC Name (1S,2R,5R,6R,9R,10R,13S,15S)-6,10-dimethyl-5-[(2R)-6-methylheptan-2-yl]-16,17-dioxapentacyclo[13.2.2.01,9.02,6.010,15]nonadec-18-en-13-ol
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C27H44O3/c1-18(2)7-6-8-19(3)21-9-10-22-24(21,4)13-12-23-25(5)14-11-20(28)17-26(25)15-16-27(22,23)30-29-26/h15-16,18-23,28H,6-14,17H2,1-5H3/t19-,20+,21-,22-,23-,24-,25-,26-,27+/m1/s1
InChI Key FOISYVRNZSWLHL-MEKQHADNSA-N
Popularity 29 references in papers

Physical and Chemical Properties

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Molecular Formula C27H44O3
Molecular Weight 416.60 g/mol
Exact Mass 416.32904526 g/mol
Topological Polar Surface Area (TPSA) 38.70 Ų
XlogP 7.20

Synonyms

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EnP(5,8)
CHEBI:65851
5alpha,8alpha-epidioxy-cholest-6-en-3beta-ol
CHEMBL453272
DTXSID101275867
LMST01010358
14231-33-5
Q27134345
(3beta,5alpha,8alpha)-5,8-Epidioxycholest-6-en-3-ol
(1S,2R,5R,6R,9R,10R,13S,15S)-6,10-dimethyl-5-[(2R)-6-methylheptan-2-yl]-16,17-dioxapentacyclo[13.2.2.01,9.02,6.010,15]nonadec-18-en-13-ol
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

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2D Structure of 5alpha,8alpha-Epidioxycholest-6-en-3beta-ol

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.88% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.64% 91.11%
CHEMBL253 P34972 Cannabinoid CB2 receptor 93.72% 97.25%
CHEMBL2179 P04062 Beta-glucocerebrosidase 92.69% 85.31%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 90.06% 94.45%
CHEMBL2581 P07339 Cathepsin D 89.87% 98.95%
CHEMBL221 P23219 Cyclooxygenase-1 89.45% 90.17%
CHEMBL3137262 O60341 LSD1/CoREST complex 88.23% 97.09%
CHEMBL268 P43235 Cathepsin K 88.13% 96.85%
CHEMBL226 P30542 Adenosine A1 receptor 87.60% 95.93%
CHEMBL3359 P21462 Formyl peptide receptor 1 87.11% 93.56%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 86.82% 82.69%
CHEMBL5608 Q16288 NT-3 growth factor receptor 86.38% 95.89%
CHEMBL2996 Q05655 Protein kinase C delta 84.98% 97.79%
CHEMBL4227 P25090 Lipoxin A4 receptor 84.09% 100.00%
CHEMBL1994 P08235 Mineralocorticoid receptor 83.88% 100.00%
CHEMBL4302 P08183 P-glycoprotein 1 83.30% 92.98%
CHEMBL2514 O95665 Neurotensin receptor 2 82.20% 100.00%
CHEMBL5103 Q969S8 Histone deacetylase 10 81.58% 90.08%
CHEMBL4618 P09960 Leukotriene A4 hydrolase 81.47% 97.86%
CHEMBL3837 P07711 Cathepsin L 81.21% 96.61%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 81.06% 95.89%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 80.97% 90.71%
CHEMBL237 P41145 Kappa opioid receptor 80.16% 98.10%
CHEMBL1806 P11388 DNA topoisomerase II alpha 80.10% 89.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 11429981
LOTUS LTS0200414
wikiData Q27134345