5alpha,8alpha-epidioxy-24E-ethylidene-cholest-6-en-3beta-ol

Details

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Internal ID 841aebf6-8408-49cf-bdfc-b16dfecd8dfb
Taxonomy Lipids and lipid-like molecules > Steroids and steroid derivatives > Stigmastanes and derivatives
IUPAC Name (1S,2R,5R,6R,9R,10R,13S,15S)-6,10-dimethyl-5-[(E,2R)-5-propan-2-ylhept-5-en-2-yl]-16,17-dioxapentacyclo[13.2.2.01,9.02,6.010,15]nonadec-18-en-13-ol
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C29H46O3/c1-7-21(19(2)3)9-8-20(4)23-10-11-24-26(23,5)14-13-25-27(6)15-12-22(30)18-28(27)16-17-29(24,25)32-31-28/h7,16-17,19-20,22-25,30H,8-15,18H2,1-6H3/b21-7+/t20-,22+,23-,24-,25-,26-,27-,28-,29+/m1/s1
InChI Key BGMWRNYOBDTZKI-AGXXPEKKSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C29H46O3
Molecular Weight 442.70 g/mol
Exact Mass 442.34469533 g/mol
Topological Polar Surface Area (TPSA) 38.70 Ų
XlogP 7.50

Synonyms

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(24E)-5alpha,8alpha-epidioxy-24-ethyl-cholesta-6,24(28)-dien-3beta-ol
LMST01040194

2D Structure

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2D Structure of 5alpha,8alpha-epidioxy-24E-ethylidene-cholest-6-en-3beta-ol

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.58% 91.11%
CHEMBL253 P34972 Cannabinoid CB2 receptor 96.73% 97.25%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.11% 96.09%
CHEMBL3137262 O60341 LSD1/CoREST complex 90.94% 97.09%
CHEMBL2581 P07339 Cathepsin D 90.56% 98.95%
CHEMBL221 P23219 Cyclooxygenase-1 89.43% 90.17%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 88.99% 94.45%
CHEMBL4835 P00338 L-lactate dehydrogenase A chain 88.67% 95.34%
CHEMBL5608 Q16288 NT-3 growth factor receptor 87.34% 95.89%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 86.28% 82.69%
CHEMBL325 Q13547 Histone deacetylase 1 85.79% 95.92%
CHEMBL4681 P42330 Aldo-keto-reductase family 1 member C3 85.52% 89.05%
CHEMBL1994 P08235 Mineralocorticoid receptor 85.24% 100.00%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 85.08% 92.62%
CHEMBL2094135 Q96BI3 Gamma-secretase 84.85% 98.05%
CHEMBL3837 P07711 Cathepsin L 84.22% 96.61%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 83.00% 95.89%
CHEMBL226 P30542 Adenosine A1 receptor 82.68% 95.93%
CHEMBL1806 P11388 DNA topoisomerase II alpha 82.67% 89.00%
CHEMBL3192 Q9BY41 Histone deacetylase 8 82.26% 93.99%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 81.01% 95.56%
CHEMBL5103 Q969S8 Histone deacetylase 10 80.66% 90.08%
CHEMBL3359 P21462 Formyl peptide receptor 1 80.36% 93.56%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 25208783
LOTUS LTS0178255
wikiData Q76513312