3-(3-Carboxy-5,6-dihydroxycyclohex-3-en-1-yl)oxycarbonyl-1-(3,4-dihydroxyphenyl)-6,7-dihydroxy-1,2-dihydronaphthalene-2-carboxylic acid

Details

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Internal ID 8460c6cb-3678-449b-b400-63277d098fcc
Taxonomy Lignans, neolignans and related compounds > Aryltetralin lignans
IUPAC Name 3-(3-carboxy-5,6-dihydroxycyclohex-3-en-1-yl)oxycarbonyl-1-(3,4-dihydroxyphenyl)-6,7-dihydroxy-1,2-dihydronaphthalene-2-carboxylic acid
SMILES (Canonical) C1C(C(C(C=C1C(=O)O)O)O)OC(=O)C2=CC3=CC(=C(C=C3C(C2C(=O)O)C4=CC(=C(C=C4)O)O)O)O
SMILES (Isomeric) C1C(C(C(C=C1C(=O)O)O)O)OC(=O)C2=CC3=CC(=C(C=C3C(C2C(=O)O)C4=CC(=C(C=C4)O)O)O)O
InChI InChI=1S/C25H22O12/c26-14-2-1-9(4-15(14)27)20-12-8-17(29)16(28)5-10(12)3-13(21(20)24(34)35)25(36)37-19-7-11(23(32)33)6-18(30)22(19)31/h1-6,8,18-22,26-31H,7H2,(H,32,33)(H,34,35)
InChI Key LZDRVVOIQKWKHP-UHFFFAOYSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C25H22O12
Molecular Weight 514.40 g/mol
Exact Mass 514.11112613 g/mol
Topological Polar Surface Area (TPSA) 222.00 Ų
XlogP 0.60

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of 3-(3-Carboxy-5,6-dihydroxycyclohex-3-en-1-yl)oxycarbonyl-1-(3,4-dihydroxyphenyl)-6,7-dihydroxy-1,2-dihydronaphthalene-2-carboxylic acid

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.64% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.46% 96.09%
CHEMBL3194 P02766 Transthyretin 93.62% 90.71%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 92.19% 99.15%
CHEMBL3137262 O60341 LSD1/CoREST complex 91.20% 97.09%
CHEMBL245 P20309 Muscarinic acetylcholine receptor M3 88.54% 97.53%
CHEMBL2035 P08912 Muscarinic acetylcholine receptor M5 87.49% 94.62%
CHEMBL5608 Q16288 NT-3 growth factor receptor 85.11% 95.89%
CHEMBL2581 P07339 Cathepsin D 83.80% 98.95%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 83.67% 95.56%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 83.60% 94.45%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 83.19% 91.71%
CHEMBL3475 P05121 Plasminogen activator inhibitor-1 83.16% 83.00%
CHEMBL216 P11229 Muscarinic acetylcholine receptor M1 82.28% 94.23%
CHEMBL211 P08172 Muscarinic acetylcholine receptor M2 81.17% 94.97%
CHEMBL340 P08684 Cytochrome P450 3A4 80.24% 91.19%
CHEMBL2535 P11166 Glucose transporter 80.11% 98.75%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Pellia epiphylla

Cross-Links

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PubChem 163002273
LOTUS LTS0075584
wikiData Q105159801