(2S,6S,8S,9R,12E,14E,16R,25R,26E)-16-ethyl-6,8,9-trihydroxy-12,25,27-trimethyl-2-propyl-1-oxa-4-azacyclooctacosa-12,14,26-triene-3,20,28-trione

Details

Top
Internal ID 82fc25f6-7dfb-4f42-938b-d058eabaf9bf
Taxonomy Phenylpropanoids and polyketides > Macrolides and analogues
IUPAC Name (2S,6S,8S,9R,12E,14E,16R,25R,26E)-16-ethyl-6,8,9-trihydroxy-12,25,27-trimethyl-2-propyl-1-oxa-4-azacyclooctacosa-12,14,26-triene-3,20,28-trione
SMILES (Canonical) CCCC1C(=O)NCC(CC(C(CCC(=CC=CC(CCCC(=O)CCCCC(C=C(C(=O)O1)C)C)CC)C)O)O)O
SMILES (Isomeric) CCC[C@H]1C(=O)NC[C@H](C[C@@H]([C@@H](CC/C(=C/C=C/[C@@H](CCCC(=O)CCCC[C@H](/C=C(/C(=O)O1)\C)C)CC)/C)O)O)O
InChI InChI=1S/C34H57NO7/c1-6-12-32-33(40)35-23-29(37)22-31(39)30(38)20-19-24(3)14-10-15-27(7-2)16-11-18-28(36)17-9-8-13-25(4)21-26(5)34(41)42-32/h10,14-15,21,25,27,29-32,37-39H,6-9,11-13,16-20,22-23H2,1-5H3,(H,35,40)/b15-10+,24-14+,26-21+/t25-,27+,29+,30-,31+,32+/m1/s1
InChI Key UDTXWYXSLGOPGK-AVLXOLRASA-N
Popularity 0 references in papers

Physical and Chemical Properties

Top
Molecular Formula C34H57NO7
Molecular Weight 591.80 g/mol
Exact Mass 591.41350316 g/mol
Topological Polar Surface Area (TPSA) 133.00 Ų
XlogP 5.90

Synonyms

Top
There are no found synonyms.

2D Structure

Top
2D Structure of (2S,6S,8S,9R,12E,14E,16R,25R,26E)-16-ethyl-6,8,9-trihydroxy-12,25,27-trimethyl-2-propyl-1-oxa-4-azacyclooctacosa-12,14,26-triene-3,20,28-trione

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL253 P34972 Cannabinoid CB2 receptor 97.66% 97.25%
CHEMBL3137262 O60341 LSD1/CoREST complex 97.19% 97.09%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.13% 96.09%
CHEMBL2581 P07339 Cathepsin D 96.72% 98.95%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 93.39% 95.56%
CHEMBL3359 P21462 Formyl peptide receptor 1 92.41% 93.56%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 87.95% 99.23%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 87.92% 91.11%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 87.58% 96.38%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 86.92% 93.03%
CHEMBL1293249 Q13887 Kruppel-like factor 5 86.70% 86.33%
CHEMBL1806 P11388 DNA topoisomerase II alpha 85.73% 89.00%
CHEMBL5103 Q969S8 Histone deacetylase 10 85.64% 90.08%
CHEMBL5608 Q16288 NT-3 growth factor receptor 85.36% 95.89%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 84.05% 95.50%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 83.50% 92.62%
CHEMBL1994 P08235 Mineralocorticoid receptor 82.79% 100.00%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 80.63% 90.71%
CHEMBL1902 P62942 FK506-binding protein 1A 80.39% 97.05%
CHEMBL226 P30542 Adenosine A1 receptor 80.09% 95.93%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

Top
PubChem 162993780
LOTUS LTS0060780
wikiData Q105270521