5-Hydroxy-3-(2-hydroxy-4-methoxyphenyl)-7-methoxy-6-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one

Details

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Internal ID 58db8568-669c-4054-9648-37d77707c401
Taxonomy Phenylpropanoids and polyketides > Isoflavonoids > O-methylated isoflavonoids > 7-O-methylated isoflavonoids
IUPAC Name 5-hydroxy-3-(2-hydroxy-4-methoxyphenyl)-7-methoxy-6-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one
SMILES (Canonical) CC(=CCC1=C(C=C2C(=C1O)C(=O)C(CO2)C3=C(C=C(C=C3)OC)O)OC)C
SMILES (Isomeric) CC(=CCC1=C(C=C2C(=C1O)C(=O)C(CO2)C3=C(C=C(C=C3)OC)O)OC)C
InChI InChI=1S/C22H24O6/c1-12(2)5-7-15-18(27-4)10-19-20(21(15)24)22(25)16(11-28-19)14-8-6-13(26-3)9-17(14)23/h5-6,8-10,16,23-24H,7,11H2,1-4H3
InChI Key KXCZKUBWRLTWBS-UHFFFAOYSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C22H24O6
Molecular Weight 384.40 g/mol
Exact Mass 384.15728848 g/mol
Topological Polar Surface Area (TPSA) 85.20 Ų
XlogP 4.80

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of 5-Hydroxy-3-(2-hydroxy-4-methoxyphenyl)-7-methoxy-6-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.57% 91.11%
CHEMBL240 Q12809 HERG 97.03% 89.76%
CHEMBL2581 P07339 Cathepsin D 95.89% 98.95%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 95.01% 94.45%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.78% 95.56%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.60% 96.09%
CHEMBL1293249 Q13887 Kruppel-like factor 5 93.19% 86.33%
CHEMBL5608 Q16288 NT-3 growth factor receptor 92.47% 95.89%
CHEMBL3060 Q9Y345 Glycine transporter 2 91.49% 99.17%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 91.49% 99.15%
CHEMBL3192 Q9BY41 Histone deacetylase 8 91.28% 93.99%
CHEMBL1929 P47989 Xanthine dehydrogenase 90.27% 96.12%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 89.73% 92.62%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 89.69% 85.14%
CHEMBL1806 P11388 DNA topoisomerase II alpha 89.48% 89.00%
CHEMBL4208 P20618 Proteasome component C5 89.04% 90.00%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 88.68% 94.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 87.27% 97.09%
CHEMBL3401 O75469 Pregnane X receptor 86.75% 94.73%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 85.75% 91.07%
CHEMBL340 P08684 Cytochrome P450 3A4 83.97% 91.19%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 83.64% 96.00%
CHEMBL226 P30542 Adenosine A1 receptor 83.42% 95.93%
CHEMBL1994 P08235 Mineralocorticoid receptor 83.33% 100.00%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 83.15% 99.23%
CHEMBL2535 P11166 Glucose transporter 82.06% 98.75%
CHEMBL3820 P35557 Hexokinase type IV 80.00% 91.96%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Glycyrrhiza aspera

Cross-Links

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PubChem 163096067
LOTUS LTS0220309
wikiData Q105147279