4,8-Dihydroxy-5-methoxy-6,10-dimethyl-4a,9a-dihydroacridin-9-one

Details

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Internal ID 19882672-6271-4420-a7d8-c252e11f5f5b
Taxonomy Organoheterocyclic compounds > Quinolines and derivatives > Benzoquinolines > Acridines
IUPAC Name 4,8-dihydroxy-5-methoxy-6,10-dimethyl-4a,9a-dihydroacridin-9-one
SMILES (Canonical) CC1=CC(=C2C(=O)C3C=CC=C(C3N(C2=C1OC)C)O)O
SMILES (Isomeric) CC1=CC(=C2C(=O)C3C=CC=C(C3N(C2=C1OC)C)O)O
InChI InChI=1S/C16H17NO4/c1-8-7-11(19)12-14(16(8)21-3)17(2)13-9(15(12)20)5-4-6-10(13)18/h4-7,9,13,18-19H,1-3H3
InChI Key BNELQOMUHVULHA-UHFFFAOYSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C16H17NO4
Molecular Weight 287.31 g/mol
Exact Mass 287.11575802 g/mol
Topological Polar Surface Area (TPSA) 70.00 Ų
XlogP 2.70

Synonyms

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9(8aH)-Acridinone, 10,10a-dihydro-1,5-dihydroxy-4-methoxy-3,10-dimethyl-

2D Structure

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2D Structure of 4,8-Dihydroxy-5-methoxy-6,10-dimethyl-4a,9a-dihydroacridin-9-one

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5697 Q9GZT9 Egl nine homolog 1 96.28% 93.40%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 93.45% 95.56%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 91.99% 96.09%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 91.92% 85.14%
CHEMBL1293249 Q13887 Kruppel-like factor 5 90.97% 86.33%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 89.89% 94.00%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 89.73% 91.11%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 88.21% 99.15%
CHEMBL4208 P20618 Proteasome component C5 85.67% 90.00%
CHEMBL2581 P07339 Cathepsin D 84.93% 98.95%
CHEMBL1951 P21397 Monoamine oxidase A 84.55% 91.49%
CHEMBL2085 P14174 Macrophage migration inhibitory factor 82.99% 80.78%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 82.95% 99.23%
CHEMBL4040 P28482 MAP kinase ERK2 82.72% 83.82%
CHEMBL5409 Q8TDU6 G-protein coupled bile acid receptor 1 81.59% 93.65%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 80.60% 93.03%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Swinglea glutinosa

Cross-Links

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PubChem 5276835
LOTUS LTS0197072
wikiData Q105100890