4-Hydroxyphenylglycine

Details

• Internal ID: cacb93c5-afa4-4b04-9a3a-fb8324e61757
• Taxonomy: Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Alpha amino acids and derivatives > Alpha amino acids
• IUPAC Name: 2-amino-2-(4-hydroxyphenyl)acetic acid
• SMILES (Canonical): C1=CC(=CC=C1C(C(=O)O)N)O
• SMILES (Isomeric): C1=CC(=CC=C1C(C(=O)O)N)O
• InChI: InChI=1S/C8H9NO3/c9-7(8(11)12)5-1-3-6(10)4-2-5/h1-4,7,10H,9H2,(H,11,12)
• InChI Key: LJCWONGJFPCTTL-UHFFFAOYSA-N
• Popularity: 133 references in papers

Physical and Chemical Properties

• Molecular Formula: C₈H₉NO₃
• Molecular Weight: 167.16 g/mol
• Exact Mass: 167.058243149 g/mol
• Topological Polar Surface Area (TPSA): 83.60 Ų
• XlogP: -2.10

Synonyms

• 4-Hydroxyphenylglycine
• (RS)-2-(4-Hydroxyphenyl)glycine
• alpha-Amino-4-hydroxybenzeneacetic acid
• 7UYG7X0F53
• CHEBI:50418
• RefChem:524066
• (+-)-ALPHA-AMINO-4-HYDROXYBENZENEACETIC ACID
• 213-353-2
• 2-azaniumyl-2-(4-hydroxyphenyl)acetate
• 938-97-6
• DL-4-Hydroxyphenylglycine
• dl-p-Hydroxyphenylglycine
• Amino(4-hydroxyphenyl)acetic acid
• MFCD00065931
• (4-hydroxyphenyl)glycine
• Benzeneacetic acid, a-amino-4-hydroxy-
• 6324-01-2
• (+/-)-alpha-Amino-4-hydroxybenzeneacetic acid
• D-(-)-4-Hydroxyphenyl-d4-glycine
• 1217854-79-9
• EINECS 213-353-2
• 2-(4-hydroxyphenyl)glycine
• (1)-4-Hydroxyphenylglycine
• UNII-7UYG7X0F53
• 4-HYDROXY-DL-PHENYLGLYCINE
• NCGC00164509-01
• 2-Amino-2-(4-hydroxyphenyl)aceticacid
• para-hydroxyphenylglycine
• 2-p-hydroxyphenylglycine
• Benzeneacetic acid, .alpha.-amino-4-hydroxy-, (.alpha.R)-
• SCHEMBL652186
• D-2-(4-Hydroxyphenyl)glycine
• SCHEMBL7196252
• SCHEMBL11443549
• DTXSID90860473
• (R)-(4-Hydroxyphenyl)glycine; (R)-2-(4-Hydroxyphenyl)glycine; 4-Hydroxy-D-phenylglycine; D-(-)-2-(4-Hydroxyphenyl)glycine; D-(-)-2-(p-Hydroxyphenyl)glycine
• amino(4-hydroxyphenyl)ethanoic acid
• NSC30081
• 2-(4-hydroxyphenylamino)acetic acid
• EINECS 228-682-7
• Amino(4-hydroxyphenyl)acetic acid #
• BBL014416
• EBC-14771
• NSC 30081
• NSC-30081
• STK391435
• AKOS000168314
• AKOS016050648
• Amino-(4-hydroxy-phenyl)-acetic acid
• AB00341
• AB02671
• CS-W005226
• DB02601
• FB-0735
• FH39249
• HY-W005226
• PB47674
• (R)-(-)-2-(4-Hydroxyphenyl)glycine
• 2-amino-2-(4-hydroxyphenyl) acetic acid
• 2-amino-2-(4-hydroxyphenyl)-acetic acid
• SY032272
• DB-014148
• (-)-alpha-amino-4-hydroxybenzeneacetic acid
• NS00081113
• ST45028861
• (R)-.alpha.-Amino-4-hydroxybenzeneacetic acid
• EN300-137921
• F11089
• F236720
• SR-01000944901
• SR-01000944901-1
• Benzeneacetic acid, .alpha.-amino-4-hydroxy-, (R)-
• BRD-A86525947-001-01-4
• Q27093571
• (+/-)-.ALPHA.-AMINO-4-HYDROXYBENZENEACETIC ACID
• Benzeneacetic acid, .alpha.-amino-4-hydroxy-, (.alpha.S)-
• L-p-Hydroxyphenylglycine,4-Hydroxy-L-phenylglycine,UK 25842

2D Structure

ADMET Properties (via admetSAR 2)

Target	Value	Probability (raw)	Probability (%)
No predicted properties yet!

Targets

Proven Targets:

No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID	UniProt ID	Name	Probability	Model accuracy
CHEMBL4040	P28482	MAP kinase ERK2	94.37%	83.82%
CHEMBL5619	P27695	DNA-(apurinic or apyrimidinic site) lyase	91.68%	91.11%
CHEMBL3251	P19838	Nuclear factor NF-kappa-B p105 subunit	88.13%	96.09%
CHEMBL4203	Q9HAZ1	Dual specificity protein kinase CLK4	87.29%	94.45%
CHEMBL3108638	O15164	Transcription intermediary factor 1-alpha	87.23%	95.56%
CHEMBL2035	P08912	Muscarinic acetylcholine receptor M5	86.85%	94.62%
CHEMBL1821	P08173	Muscarinic acetylcholine receptor M4	83.27%	94.08%
CHEMBL2581	P07339	Cathepsin D	83.26%	98.95%
CHEMBL3060	Q9Y345	Glycine transporter 2	82.33%	99.17%
CHEMBL1860	P10827	Thyroid hormone receptor alpha	82.13%	99.15%

Plants that contains it

There are no matching plants.

Cross-Links

• PubChem: 92143
• LOTUS: LTS0071625
• wikiData: Q27093571