Meridianin C

Details

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Internal ID 6cd17f5f-4644-44b4-a34b-812b984d38ea
Taxonomy Organoheterocyclic compounds > Indoles and derivatives > Indoles
IUPAC Name 4-(5-bromo-1H-indol-3-yl)pyrimidin-2-amine
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C12H9BrN4/c13-7-1-2-10-8(5-7)9(6-16-10)11-3-4-15-12(14)17-11/h1-6,16H,(H2,14,15,17)
InChI Key PKQJCYXKRNGUKQ-UHFFFAOYSA-N
Popularity 18 references in papers

Physical and Chemical Properties

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Molecular Formula C12H9BrN4
Molecular Weight 289.13 g/mol
Exact Mass 288.00106 g/mol
Topological Polar Surface Area (TPSA) 67.60 Ų
XlogP 2.30

Synonyms

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213473-00-8
Meridianin C
2-Pyrimidinamine, 4-(5-bromo-1H-indol-3-yl)-
CHEMBL44541
SCHEMBL1612228
BDBM10840
DTXSID50434275
PKQJCYXKRNGUKQ-UHFFFAOYSA-N
MFCD22552582
AKOS027469387
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

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2D Structure of Meridianin C

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
CHEMBL4224 P49759 Dual specificty protein kinase CLK1 220 nM
IC50
via Super-PRED

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5443 O00311 Cell division cycle 7-related protein kinase 99.87% 96.11%
CHEMBL1951 P21397 Monoamine oxidase A 97.77% 91.49%
CHEMBL2292 Q13627 Dual-specificity tyrosine-phosphorylation regulated kinase 1A 95.85% 93.24%
CHEMBL3038469 P24941 CDK2/Cyclin A 95.15% 91.38%
CHEMBL5543 Q9Y463 Dual specificity tyrosine-phosphorylation-regulated kinase 1B 94.33% 94.70%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 93.24% 94.00%
CHEMBL241 Q14432 Phosphodiesterase 3A 92.51% 92.94%
CHEMBL225 P28335 Serotonin 2c (5-HT2c) receptor 91.81% 89.62%
CHEMBL4101 P17612 cAMP-dependent protein kinase alpha-catalytic subunit 90.93% 82.86%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 90.70% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 89.28% 96.09%
CHEMBL2535 P11166 Glucose transporter 87.67% 98.75%
CHEMBL3959 P16083 Quinone reductase 2 87.51% 89.49%
CHEMBL2094127 P06493 Cyclin-dependent kinase 1/cyclin B 86.61% 96.00%
CHEMBL4145 Q9UKV0 Histone deacetylase 9 86.29% 85.49%
CHEMBL2378 P30307 Dual specificity phosphatase Cdc25C 83.94% 96.67%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 83.76% 100.00%
CHEMBL1781 P11387 DNA topoisomerase I 83.73% 97.00%
CHEMBL240 Q12809 HERG 83.21% 89.76%
CHEMBL308 P06493 Cyclin-dependent kinase 1 82.99% 91.73%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 82.84% 93.03%
CHEMBL5608 Q16288 NT-3 growth factor receptor 81.89% 95.89%
CHEMBL4158 P49327 Fatty acid synthase 81.31% 82.50%
CHEMBL2095226 P05556 Integrin alpha-5/beta-1 80.85% 96.39%
CHEMBL213 P08588 Beta-1 adrenergic receptor 80.78% 95.56%
CHEMBL4816 Q9Y243 Serine/threonine-protein kinase AKT3 80.75% 96.28%
CHEMBL1811 P34995 Prostanoid EP1 receptor 80.40% 95.71%
CHEMBL2094121 P14867 GABA-A receptor; alpha-1/beta-3/gamma-2 80.13% 95.50%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 10017019
LOTUS LTS0073686
wikiData Q82248635