4-(3,4-Dimethoxybenzyl)-3-(4-hydroxy-3,5-dimethoxybenzyl)dihydro-2(3H)-furanone

Details

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Internal ID 1434be27-4f45-40af-a221-b09004f43dfa
Taxonomy Lignans, neolignans and related compounds > Furanoid lignans > Tetrahydrofuran lignans > 9,9-epoxylignans > Dibenzylbutyrolactone lignans
IUPAC Name 4-[(3,4-dimethoxyphenyl)methyl]-3-[(4-hydroxy-3,5-dimethoxyphenyl)methyl]oxolan-2-one
SMILES (Canonical) COC1=C(C=C(C=C1)CC2COC(=O)C2CC3=CC(=C(C(=C3)OC)O)OC)OC
SMILES (Isomeric) COC1=C(C=C(C=C1)CC2COC(=O)C2CC3=CC(=C(C(=C3)OC)O)OC)OC
InChI InChI=1S/C22H26O7/c1-25-17-6-5-13(9-18(17)26-2)7-15-12-29-22(24)16(15)8-14-10-19(27-3)21(23)20(11-14)28-4/h5-6,9-11,15-16,23H,7-8,12H2,1-4H3
InChI Key IWOQKLIGANPQAU-UHFFFAOYSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C22H26O7
Molecular Weight 402.40 g/mol
Exact Mass 402.16785316 g/mol
Topological Polar Surface Area (TPSA) 83.40 Ų
XlogP 3.60

Synonyms

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4-(3,4-Dimethoxybenzyl)-3-(4-hydroxy-3,5-dimethoxybenzyl)dihydro-2(3H)-furanone
4-[(3,4-dimethoxyphenyl)methyl]-3-[(4-hydroxy-3,5-dimethoxy-phenyl)methyl]tetrahydrofuran-2-one

2D Structure

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2D Structure of 4-(3,4-Dimethoxybenzyl)-3-(4-hydroxy-3,5-dimethoxybenzyl)dihydro-2(3H)-furanone

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.32% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.14% 96.09%
CHEMBL4040 P28482 MAP kinase ERK2 96.72% 83.82%
CHEMBL2581 P07339 Cathepsin D 96.29% 98.95%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 93.45% 94.45%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 91.81% 85.14%
CHEMBL1293249 Q13887 Kruppel-like factor 5 91.10% 86.33%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 89.71% 92.62%
CHEMBL5608 Q16288 NT-3 growth factor receptor 89.12% 95.89%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 87.53% 94.00%
CHEMBL3060 Q9Y345 Glycine transporter 2 87.46% 99.17%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 86.14% 95.56%
CHEMBL1255126 O15151 Protein Mdm4 84.10% 90.20%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 83.54% 95.89%
CHEMBL1806 P11388 DNA topoisomerase II alpha 82.44% 89.00%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 82.26% 96.00%
CHEMBL241 Q14432 Phosphodiesterase 3A 81.33% 92.94%
CHEMBL3401 O75469 Pregnane X receptor 80.64% 94.73%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Virola elongata

Cross-Links

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PubChem 495972
LOTUS LTS0080427
wikiData Q105121772