(3s,6s)-3-(4-Hydroxybenzyl)-6-(1h-Indol-3-Ylmethyl)piperazine-2,5-Dione

Details

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Internal ID 28f47f8e-7cf0-42e6-92de-d4351f35e7c9
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Alpha amino acids and derivatives
IUPAC Name (3S,6S)-3-[(4-hydroxyphenyl)methyl]-6-(1H-indol-3-ylmethyl)piperazine-2,5-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C20H19N3O3/c24-14-7-5-12(6-8-14)9-17-19(25)23-18(20(26)22-17)10-13-11-21-16-4-2-1-3-15(13)16/h1-8,11,17-18,21,24H,9-10H2,(H,22,26)(H,23,25)/t17-,18-/m0/s1
InChI Key ZJDMXAAEAVGGSK-ROUUACIJSA-N
Popularity 7 references in papers

Physical and Chemical Properties

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Molecular Formula C20H19N3O3
Molecular Weight 349.40 g/mol
Exact Mass 349.14264148 g/mol
Topological Polar Surface Area (TPSA) 94.20 Ų
XlogP 2.40

Synonyms

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20829-53-2
(3s,6s)-3-(4-Hydroxybenzyl)-6-(1h-Indol-3-Ylmethyl)piperazine-2,5-Dione
(3S,6S)-3-((1H-indol-3-yl)methyl)-6-(4-hydroxybenzyl)piperazine-2,5-dione
(3S,6S)-3-[(4-hydroxyphenyl)methyl]-6-(1H-indol-3-ylmethyl)piperazine-2,5-dione
Cyclo-L-Trp-L-Tyr
cyclo(L-Tyr-L-Trp)
CHEMBL191476
MFCD00083829
J-013664
Q27452040
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

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2D Structure of (3s,6s)-3-(4-Hydroxybenzyl)-6-(1h-Indol-3-Ylmethyl)piperazine-2,5-Dione

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.27% 91.11%
CHEMBL4040 P28482 MAP kinase ERK2 95.72% 83.82%
CHEMBL2581 P07339 Cathepsin D 95.33% 98.95%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 93.99% 95.56%
CHEMBL3310 Q96DB2 Histone deacetylase 11 93.38% 88.56%
CHEMBL5103 Q969S8 Histone deacetylase 10 92.55% 90.08%
CHEMBL1951 P21397 Monoamine oxidase A 92.53% 91.49%
CHEMBL2035 P08912 Muscarinic acetylcholine receptor M5 91.54% 94.62%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 90.17% 97.64%
CHEMBL3830 Q2M2I8 Adaptor-associated kinase 89.77% 83.10%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 89.47% 92.62%
CHEMBL1937 Q92769 Histone deacetylase 2 88.98% 94.75%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 87.65% 96.09%
CHEMBL3192 Q9BY41 Histone deacetylase 8 87.64% 93.99%
CHEMBL2535 P11166 Glucose transporter 87.25% 98.75%
CHEMBL2095172 P14867 GABA-A receptor; alpha-1/beta-2/gamma-2 85.76% 92.67%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 85.21% 94.45%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 85.20% 94.00%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 84.90% 91.71%
CHEMBL5966 P55899 IgG receptor FcRn large subunit p51 83.49% 90.93%
CHEMBL1806 P11388 DNA topoisomerase II alpha 82.73% 89.00%
CHEMBL213 P08588 Beta-1 adrenergic receptor 82.68% 95.56%
CHEMBL1293287 P14735 Insulin-degrading enzyme 82.55% 88.10%
CHEMBL2563 Q9UQL6 Histone deacetylase 5 82.52% 89.67%
CHEMBL255 P29275 Adenosine A2b receptor 81.86% 98.59%
CHEMBL3137262 O60341 LSD1/CoREST complex 81.86% 97.09%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 80.14% 95.50%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 7408259
LOTUS LTS0206964
wikiData Q27452040