3beta,9alpha,14alpha-trihydroxy-(22E,24R)-ergost-22-en-7-one

Details

Top
Internal ID 089e8075-17fc-4af7-ba58-bf4d0272c649
Taxonomy Lipids and lipid-like molecules > Steroids and steroid derivatives > Ergostane steroids > Ergosterols and derivatives
IUPAC Name (3S,9R,10S,13R,14R,17S)-17-[(E,5R)-5,6-dimethylhept-3-en-2-yl]-3,9,14-trihydroxy-10,13-dimethyl-1,2,3,4,5,6,8,11,12,15,16,17-dodecahydrocyclopenta[a]phenanthren-7-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C28H46O4/c1-17(2)18(3)7-8-19(4)22-10-12-27(31)24-23(30)16-20-15-21(29)9-11-25(20,5)28(24,32)14-13-26(22,27)6/h7-8,17-22,24,29,31-32H,9-16H2,1-6H3/b8-7+/t18-,19?,20?,21-,22-,24?,25-,26+,27+,28+/m0/s1
InChI Key HYGBHWPLEUKJIK-LUMGQHEXSA-N
Popularity 2 references in papers

Physical and Chemical Properties

Top
Molecular Formula C28H46O4
Molecular Weight 446.70 g/mol
Exact Mass 446.33960994 g/mol
Topological Polar Surface Area (TPSA) 77.80 Ų
XlogP 4.40

Synonyms

Top
(3S,9R,10S,13R,14R,17S)-17-((E,5R)-5,6-dimethylhept-3-en-2-yl)-3,9,14-trihydroxy-10,13-dimethyl-1,2,3,4,5,6,8,11,12,15,16,17-dodecahydrocyclopenta(a)phenanthren-7-one
(3S,9R,10S,13R,14R,17S)-17-[(E,5R)-5,6-dimethylhept-3-en-2-yl]-3,9,14-trihydroxy-10,13-dimethyl-1,2,3,4,5,6,8,11,12,15,16,17-dodecahydrocyclopenta[a]phenanthren-7-one
RefChem:95640
CHEBI:218628

2D Structure

Top
2D Structure of 3beta,9alpha,14alpha-trihydroxy-(22E,24R)-ergost-22-en-7-one

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 94.50% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 93.77% 95.56%
CHEMBL2581 P07339 Cathepsin D 93.47% 98.95%
CHEMBL253 P34972 Cannabinoid CB2 receptor 93.40% 97.25%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 92.80% 82.69%
CHEMBL3137262 O60341 LSD1/CoREST complex 90.61% 97.09%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 89.04% 96.09%
CHEMBL5608 Q16288 NT-3 growth factor receptor 87.03% 95.89%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 86.91% 92.88%
CHEMBL238 Q01959 Dopamine transporter 85.84% 95.88%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 85.65% 94.45%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 84.85% 97.14%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 83.72% 91.07%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 83.16% 99.23%
CHEMBL1902 P62942 FK506-binding protein 1A 82.18% 97.05%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 80.75% 93.03%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

Top
PubChem 139591370
LOTUS LTS0071600
wikiData Q105035299