3beta,11alpha-Dihydroxyergosta-8,24(28)-dien-7-one

Details

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Internal ID 5e11f55b-56e7-4e39-b5a1-4c29c137a36c
Taxonomy Lipids and lipid-like molecules > Steroids and steroid derivatives > Ergostane steroids > Ergosterols and derivatives
IUPAC Name (3S,5R,10S,11R,13R,14R,17R)-3,11-dihydroxy-10,13-dimethyl-17-[(2R)-6-methyl-5-methylideneheptan-2-yl]-1,2,3,4,5,6,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-7-one
SMILES (Canonical) CC(C)C(=C)CCC(C)C1CCC2C1(CC(C3=C2C(=O)CC4C3(CCC(C4)O)C)O)C
SMILES (Isomeric) C[C@H](CCC(=C)C(C)C)[C@H]1CC[C@@H]2[C@@]1(C[C@H](C3=C2C(=O)C[C@@H]4[C@@]3(CC[C@@H](C4)O)C)O)C
InChI InChI=1S/C28H44O3/c1-16(2)17(3)7-8-18(4)21-9-10-22-25-23(30)14-19-13-20(29)11-12-27(19,5)26(25)24(31)15-28(21,22)6/h16,18-22,24,29,31H,3,7-15H2,1-2,4-6H3/t18-,19-,20+,21-,22+,24-,27+,28-/m1/s1
InChI Key IWSQIMKLMWQADE-MOKAYLCWSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C28H44O3
Molecular Weight 428.60 g/mol
Exact Mass 428.32904526 g/mol
Topological Polar Surface Area (TPSA) 57.50 Ų
XlogP 5.80

Synonyms

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3beta,11alpha-dihydroxyergosta-8,24(28)-dien-7-one
(3beta,5alpha,11alpha)-3,11-dihydroxyergosta-8,24(28)-dien-7-one
CHEMBL1631980
DTXSID101214168
1256843-32-9
Q27138674

2D Structure

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2D Structure of 3beta,11alpha-Dihydroxyergosta-8,24(28)-dien-7-one

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL253 P34972 Cannabinoid CB2 receptor 98.74% 97.25%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 96.62% 94.45%
CHEMBL3137262 O60341 LSD1/CoREST complex 94.75% 97.09%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.46% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 94.18% 91.11%
CHEMBL2581 P07339 Cathepsin D 93.02% 98.95%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 91.49% 82.69%
CHEMBL221 P23219 Cyclooxygenase-1 89.79% 90.17%
CHEMBL1994 P08235 Mineralocorticoid receptor 88.01% 100.00%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 87.59% 90.71%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 86.60% 93.04%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 86.14% 92.62%
CHEMBL2179 P04062 Beta-glucocerebrosidase 85.92% 85.31%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 85.59% 95.89%
CHEMBL218 P21554 Cannabinoid CB1 receptor 85.02% 96.61%
CHEMBL5608 Q16288 NT-3 growth factor receptor 84.64% 95.89%
CHEMBL2842 P42345 Serine/threonine-protein kinase mTOR 83.14% 92.78%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 82.80% 95.56%
CHEMBL1907602 P06493 Cyclin-dependent kinase 1/cyclin B1 82.52% 91.24%
CHEMBL1871 P10275 Androgen Receptor 82.47% 96.43%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 81.82% 93.03%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 81.39% 92.88%
CHEMBL3746 P80365 11-beta-hydroxysteroid dehydrogenase 2 81.35% 94.78%
CHEMBL4681 P42330 Aldo-keto-reductase family 1 member C3 80.87% 89.05%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 50899855
LOTUS LTS0071001
wikiData Q27138674