Cyanopeptolin CP992

Details

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Internal ID 36549b6b-242c-4622-9dce-e79056684ada
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name 4-[[15-(5-amino-5-iminopentyl)-2-benzyl-21-hydroxy-5-[2-(4-hydroxyphenyl)ethyl]-4,11-dimethyl-3,6,9,13,16,22-hexaoxo-8-propan-2-yl-10-oxa-1,4,7,14,17-pentazabicyclo[16.3.1]docosan-12-yl]amino]-3-(butanoylamino)-4-oxobutanoic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C49H69N9O13/c1-6-12-38(60)52-34(26-40(62)63)44(65)56-42-28(4)71-49(70)41(27(2)3)55-45(66)35(23-19-29-17-20-31(59)21-18-29)57(5)48(69)36(25-30-13-8-7-9-14-30)58-39(61)24-22-33(47(58)68)54-43(64)32(53-46(42)67)15-10-11-16-37(50)51/h7-9,13-14,17-18,20-21,27-28,32-36,39,41-42,59,61H,6,10-12,15-16,19,22-26H2,1-5H3,(H3,50,51)(H,52,60)(H,53,67)(H,54,64)(H,55,66)(H,56,65)(H,62,63)
InChI Key HPCHIRZLXVDCJR-UHFFFAOYSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C49H69N9O13
Molecular Weight 992.10 g/mol
Exact Mass 991.50148329 g/mol
Topological Polar Surface Area (TPSA) 340.00 Ų
XlogP 1.90

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Cyanopeptolin CP992

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.95% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.23% 96.09%
CHEMBL4040 P28482 MAP kinase ERK2 98.87% 83.82%
CHEMBL3060 Q9Y345 Glycine transporter 2 98.39% 99.17%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.33% 91.11%
CHEMBL221 P23219 Cyclooxygenase-1 95.63% 90.17%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 95.26% 94.45%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.88% 95.56%
CHEMBL5103 Q969S8 Histone deacetylase 10 93.11% 90.08%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 91.49% 97.64%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 91.43% 95.89%
CHEMBL3137262 O60341 LSD1/CoREST complex 90.11% 97.09%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 89.90% 99.23%
CHEMBL1293249 Q13887 Kruppel-like factor 5 89.61% 86.33%
CHEMBL5608 Q16288 NT-3 growth factor receptor 89.17% 95.89%
CHEMBL1806 P11388 DNA topoisomerase II alpha 89.05% 89.00%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 88.95% 93.00%
CHEMBL226 P30542 Adenosine A1 receptor 88.91% 95.93%
CHEMBL1949 P62937 Cyclophilin A 88.79% 98.57%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 88.49% 97.14%
CHEMBL5939 Q9NZ08 Endoplasmic reticulum aminopeptidase 1 88.11% 100.00%
CHEMBL236 P41143 Delta opioid receptor 87.90% 99.35%
CHEMBL4769 O95749 Geranylgeranyl pyrophosphate synthetase 87.62% 92.08%
CHEMBL4072 P07858 Cathepsin B 87.14% 93.67%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 86.62% 90.71%
CHEMBL3891 P07384 Calpain 1 86.32% 93.04%
CHEMBL3776 Q14790 Caspase-8 85.13% 97.06%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 84.21% 95.00%
CHEMBL3359 P21462 Formyl peptide receptor 1 83.88% 93.56%
CHEMBL3713062 P10646 Tissue factor pathway inhibitor 83.23% 97.33%
CHEMBL2535 P11166 Glucose transporter 83.10% 98.75%
CHEMBL340 P08684 Cytochrome P450 3A4 83.08% 91.19%
CHEMBL4394 Q9NYA1 Sphingosine kinase 1 82.09% 96.03%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 81.04% 82.38%
CHEMBL255 P29275 Adenosine A2b receptor 80.91% 98.59%
CHEMBL3468 P55210 Caspase-7 80.89% 95.68%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 80.74% 96.47%
CHEMBL1293287 P14735 Insulin-degrading enzyme 80.22% 88.10%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 146682045
LOTUS LTS0134809
wikiData Q105031632