3alpha,7beta-Dihydroxy-5beta,6beta-epoxycholestane

Details

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Internal ID 449ecc4c-5913-4629-923d-012a48ecb763
Taxonomy Lipids and lipid-like molecules > Steroids and steroid derivatives > Cholestane steroids > Cholesterols and derivatives
IUPAC Name 2,16-dimethyl-15-(6-methylheptan-2-yl)-8-oxapentacyclo[9.7.0.02,7.07,9.012,16]octadecane-5,10-diol
SMILES (Canonical) CC(C)CCCC(C)C1CCC2C1(CCC3C2C(C4C5(C3(CCC(C5)O)C)O4)O)C
SMILES (Isomeric) CC(C)CCCC(C)C1CCC2C1(CCC3C2C(C4C5(C3(CCC(C5)O)C)O4)O)C
InChI InChI=1S/C27H46O3/c1-16(2)7-6-8-17(3)19-9-10-20-22-21(12-13-25(19,20)4)26(5)14-11-18(28)15-27(26)24(30-27)23(22)29/h16-24,28-29H,6-15H2,1-5H3
InChI Key NFSVGWISRPLYOZ-UHFFFAOYSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C27H46O3
Molecular Weight 418.70 g/mol
Exact Mass 418.34469533 g/mol
Topological Polar Surface Area (TPSA) 53.00 Ų
XlogP 7.00

Synonyms

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3.alpha.,7.beta.-Dihydroxy-5.beta.,6.beta.-epoxycholestane
9-(1,5-Dimethylhexyl)-9a,11b-dimethylhexadecahydrocyclopenta[1,2]phenanthro[8a,9-b]oxirene-3,6-diol #

2D Structure

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2D Structure of 3alpha,7beta-Dihydroxy-5beta,6beta-epoxycholestane

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.16% 96.09%
CHEMBL2179 P04062 Beta-glucocerebrosidase 96.82% 85.31%
CHEMBL253 P34972 Cannabinoid CB2 receptor 96.00% 97.25%
CHEMBL226 P30542 Adenosine A1 receptor 95.09% 95.93%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 94.66% 94.45%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 94.43% 91.11%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 92.38% 95.89%
CHEMBL3137262 O60341 LSD1/CoREST complex 91.00% 97.09%
CHEMBL4681 P42330 Aldo-keto-reductase family 1 member C3 90.02% 89.05%
CHEMBL3837 P07711 Cathepsin L 89.77% 96.61%
CHEMBL3359 P21462 Formyl peptide receptor 1 88.31% 93.56%
CHEMBL1994 P08235 Mineralocorticoid receptor 88.22% 100.00%
CHEMBL4302 P08183 P-glycoprotein 1 88.08% 92.98%
CHEMBL5608 Q16288 NT-3 growth factor receptor 87.86% 95.89%
CHEMBL2094135 Q96BI3 Gamma-secretase 87.83% 98.05%
CHEMBL2581 P07339 Cathepsin D 87.79% 98.95%
CHEMBL237 P41145 Kappa opioid receptor 86.74% 98.10%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 85.84% 92.62%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 85.15% 90.71%
CHEMBL4227 P25090 Lipoxin A4 receptor 84.89% 100.00%
CHEMBL221 P23219 Cyclooxygenase-1 83.81% 90.17%
CHEMBL1871 P10275 Androgen Receptor 83.49% 96.43%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 82.03% 82.69%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 82.01% 97.14%
CHEMBL2955 O95136 Sphingosine 1-phosphate receptor Edg-5 81.98% 92.86%
CHEMBL2959 Q08881 Tyrosine-protein kinase ITK/TSK 81.77% 95.00%
CHEMBL4618 P09960 Leukotriene A4 hydrolase 81.15% 97.86%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 80.76% 96.38%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 579361
LOTUS LTS0009898
wikiData Q105178661