3,5,15,17-O-Tetraacetyl-7-O-nicotinoylcheiradone

Details

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Internal ID 8ac61dd2-a51c-4456-8764-29fc757d32f8
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Pentacarboxylic acids and derivatives
IUPAC Name [(1R,2R,3R,4S,5S,7R,9S,12S,15R,16R)-2,4,7-triacetyloxy-1-(acetyloxymethyl)-5,9,11,11-tetramethyl-8-oxo-10-oxatetracyclo[7.6.1.03,7.012,16]hexadec-13-en-15-yl] pyridine-3-carboxylate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C34H41NO12/c1-17-14-34(46-21(5)39)25(26(17)43-19(3)37)28(44-20(4)38)33(16-42-18(2)36)24(45-29(40)22-10-9-13-35-15-22)12-11-23-27(33)32(8,30(34)41)47-31(23,6)7/h9-13,15,17,23-28H,14,16H2,1-8H3/t17-,23-,24+,25+,26-,27-,28+,32-,33+,34+/m0/s1
InChI Key DHOFOOLUGSPOFF-FSHZCWIOSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C34H41NO12
Molecular Weight 655.70 g/mol
Exact Mass 655.26287574 g/mol
Topological Polar Surface Area (TPSA) 171.00 Ų
XlogP 2.40

Synonyms

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((1R,2R,3R,4S,5S,7R,9S,12S,15R,16R)-2,4,7-triacetyloxy-1-(acetyloxymethyl)-5,9,11,11-tetramethyl-8-oxo-10-oxatetracyclo(7.6.1.03,7.012,16)hexadec-13-en-15-yl) pyridine-3-carboxylate
[(1R,2R,3R,4S,5S,7R,9S,12S,15R,16R)-2,4,7-Triacetyloxy-1-(acetyloxymethyl)-5,9,11,11-tetramethyl-8-oxo-10-oxatetracyclo[7.6.1.03,7.012,16]hexadec-13-en-15-yl] pyridine-3-carboxylate
TANC CPD
RefChem:91287

2D Structure

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2D Structure of 3,5,15,17-O-Tetraacetyl-7-O-nicotinoylcheiradone

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.37% 96.09%
CHEMBL1293249 Q13887 Kruppel-like factor 5 98.36% 86.33%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 97.28% 85.14%
CHEMBL2581 P07339 Cathepsin D 97.06% 98.95%
CHEMBL1293267 Q9HC97 G-protein coupled receptor 35 91.89% 89.34%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 90.95% 99.23%
CHEMBL1293277 O15118 Niemann-Pick C1 protein 90.11% 81.11%
CHEMBL2996 Q05655 Protein kinase C delta 90.08% 97.79%
CHEMBL253 P34972 Cannabinoid CB2 receptor 87.90% 97.25%
CHEMBL1951 P21397 Monoamine oxidase A 87.09% 91.49%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 86.14% 91.07%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 85.48% 94.00%
CHEMBL2094127 P06493 Cyclin-dependent kinase 1/cyclin B 85.37% 96.00%
CHEMBL5028 O14672 ADAM10 85.17% 97.50%
CHEMBL1806 P11388 DNA topoisomerase II alpha 84.85% 89.00%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 84.56% 91.11%
CHEMBL335 P18031 Protein-tyrosine phosphatase 1B 84.27% 95.17%
CHEMBL5608 Q16288 NT-3 growth factor receptor 84.09% 95.89%
CHEMBL4040 P28482 MAP kinase ERK2 83.85% 83.82%
CHEMBL2107 P61073 C-X-C chemokine receptor type 4 82.62% 93.10%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 81.69% 94.80%
CHEMBL2378 P30307 Dual specificity phosphatase Cdc25C 81.67% 96.67%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 81.34% 82.69%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 80.77% 94.45%
CHEMBL4208 P20618 Proteasome component C5 80.55% 90.00%
CHEMBL3864 Q06124 Protein-tyrosine phosphatase 2C 80.31% 94.42%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Euphorbia polycaulis

Cross-Links

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PubChem 10865221
LOTUS LTS0074574
wikiData Q104980541