(4aR,10aS)-5,8-dihydroxy-6-methoxy-1,1-dimethyl-9-oxo-7-propan-2-yl-3,4,10,10a-tetrahydro-2H-phenanthrene-4a-carbaldehyde

Details

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Internal ID b55c466b-f76d-4092-964c-a986485bdf64
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Diterpenoids
IUPAC Name (4aR,10aS)-5,8-dihydroxy-6-methoxy-1,1-dimethyl-9-oxo-7-propan-2-yl-3,4,10,10a-tetrahydro-2H-phenanthrene-4a-carbaldehyde
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C21H28O5/c1-11(2)14-17(24)15-12(23)9-13-20(3,4)7-6-8-21(13,10-22)16(15)18(25)19(14)26-5/h10-11,13,24-25H,6-9H2,1-5H3/t13-,21+/m0/s1
InChI Key HQAUIUZXOVTQKQ-YEJXKQKISA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C21H28O5
Molecular Weight 360.40 g/mol
Exact Mass 360.19367399 g/mol
Topological Polar Surface Area (TPSA) 83.80 Ų
XlogP 4.30

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of (4aR,10aS)-5,8-dihydroxy-6-methoxy-1,1-dimethyl-9-oxo-7-propan-2-yl-3,4,10,10a-tetrahydro-2H-phenanthrene-4a-carbaldehyde

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.51% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 98.43% 94.45%
CHEMBL2581 P07339 Cathepsin D 95.17% 98.95%
CHEMBL1937 Q92769 Histone deacetylase 2 94.08% 94.75%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 93.30% 95.56%
CHEMBL253 P34972 Cannabinoid CB2 receptor 91.65% 97.25%
CHEMBL3359 P21462 Formyl peptide receptor 1 91.25% 93.56%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 90.04% 96.09%
CHEMBL3192 Q9BY41 Histone deacetylase 8 88.29% 93.99%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 87.50% 90.71%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 86.66% 99.23%
CHEMBL233 P35372 Mu opioid receptor 85.70% 97.93%
CHEMBL5608 Q16288 NT-3 growth factor receptor 85.37% 95.89%
CHEMBL340 P08684 Cytochrome P450 3A4 84.28% 91.19%
CHEMBL4040 P28482 MAP kinase ERK2 83.86% 83.82%
CHEMBL1293249 Q13887 Kruppel-like factor 5 83.66% 86.33%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 83.58% 96.77%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 83.45% 96.21%
CHEMBL4072 P07858 Cathepsin B 82.84% 93.67%
CHEMBL3137262 O60341 LSD1/CoREST complex 82.67% 97.09%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 82.23% 92.62%
CHEMBL3430907 Q96GD4 Aurora kinase B/Inner centromere protein 81.86% 97.50%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 81.70% 82.69%
CHEMBL1821 P08173 Muscarinic acetylcholine receptor M4 81.52% 94.08%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 81.35% 99.15%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 81.21% 91.07%
CHEMBL215 P09917 Arachidonate 5-lipoxygenase 80.84% 92.68%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Salvia coulteri

Cross-Links

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PubChem 101665854
LOTUS LTS0125934
wikiData Q105032142