3,22-Dihydroxyergost-5-en-7-one

Details

Top
Internal ID f099d357-312c-40b8-bd07-812c7455923d
Taxonomy Lipids and lipid-like molecules > Steroids and steroid derivatives > Bile acids, alcohols and derivatives > Hydroxy bile acids, alcohols and derivatives > Dihydroxy bile acids, alcohols and derivatives
IUPAC Name 3-hydroxy-17-(3-hydroxy-5,6-dimethylheptan-2-yl)-10,13-dimethyl-1,2,3,4,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-7-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C28H46O3/c1-16(2)17(3)13-24(30)18(4)21-7-8-22-26-23(10-12-28(21,22)6)27(5)11-9-20(29)14-19(27)15-25(26)31/h15-18,20-24,26,29-30H,7-14H2,1-6H3
InChI Key PKESXWKAOMUZDM-UHFFFAOYSA-N
Popularity 4 references in papers

Physical and Chemical Properties

Top
Molecular Formula C28H46O3
Molecular Weight 430.70 g/mol
Exact Mass 430.34469533 g/mol
Topological Polar Surface Area (TPSA) 57.50 Ų
XlogP 6.40

Synonyms

Top
3,22-Dihydroxy-24-methylcholest-5-en-7-one

2D Structure

Top
2D Structure of 3,22-Dihydroxyergost-5-en-7-one

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL226 P30542 Adenosine A1 receptor 98.47% 95.93%
CHEMBL2581 P07339 Cathepsin D 98.18% 98.95%
CHEMBL253 P34972 Cannabinoid CB2 receptor 97.68% 97.25%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.63% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.40% 91.11%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 92.17% 90.71%
CHEMBL1994 P08235 Mineralocorticoid receptor 92.10% 100.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 89.90% 95.89%
CHEMBL3137262 O60341 LSD1/CoREST complex 89.22% 97.09%
CHEMBL255 P29275 Adenosine A2b receptor 88.21% 98.59%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 85.56% 95.56%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 85.40% 95.89%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 84.91% 93.04%
CHEMBL4208 P20618 Proteasome component C5 84.13% 90.00%
CHEMBL1806 P11388 DNA topoisomerase II alpha 83.93% 89.00%
CHEMBL240 Q12809 HERG 81.65% 89.76%
CHEMBL1293249 Q13887 Kruppel-like factor 5 80.90% 86.33%
CHEMBL1871 P10275 Androgen Receptor 80.47% 96.43%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Schleichera oleosa

Cross-Links

Top
PubChem 75048831
LOTUS LTS0067687
wikiData Q105210381