3,10-dimethoxy-8-methyl-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-2,11-diol
| Internal ID | 9ae2d463-535a-4c7a-ae95-e8e94e9bf991 |
| Taxonomy | Alkaloids and derivatives > Protoberberine alkaloids and derivatives |
| IUPAC Name | 3,10-dimethoxy-8-methyl-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-2,11-diol |
| SMILES (Canonical) | |
| SMILES (Isomeric) | |
| InChI | InChI=1S/C20H23NO4/c1-11-14-10-20(25-3)17(22)7-13(14)6-16-15-9-18(23)19(24-2)8-12(15)4-5-21(11)16/h7-11,16,22-23H,4-6H2,1-3H3 |
| InChI Key | ZXKBEZWHVKPZSF-UHFFFAOYSA-N |
| Popularity | 2 references in papers |
| Molecular Formula | C20H23NO4 |
| Molecular Weight | 341.40 g/mol |
| Exact Mass | 341.16270821 g/mol |
| Topological Polar Surface Area (TPSA) | 62.20 Ų |
| XlogP | 3.00 |
| There are no found synonyms. |
![2D Structure of 3,10-dimethoxy-8-methyl-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-2,11-diol](https://plantaedb.com/storage/docs/compounds/2023/11/310-dimethoxy-8-methyl-681313a-tetrahydro-5h-isoquinolino21-bisoquinoline-211-diol.jpg "2D Structure of 3,10-dimethoxy-8-methyl-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-2,11-diol")
| Target | Value | Probability (raw) | Probability (%) |
|---|---|---|---|
| No predicted properties yet! | |||
Proven Targets:
| CHEMBL ID | UniProt ID | Name | Min activity | Assay type | Source |
|---|---|---|---|---|---|
| No proven targets yet! | |||||
Predicted Targets (via Super-PRED):
| CHEMBL ID | UniProt ID | Name | Probability | Model accuracy |
|---|---|---|---|---|
| CHEMBL3251 | P19838 | Nuclear factor NF-kappa-B p105 subunit | 99.05% | 96.09% |
| CHEMBL5619 | P27695 | DNA-(apurinic or apyrimidinic site) lyase | 96.82% | 91.11% |
| CHEMBL4261 | Q16665 | Hypoxia-inducible factor 1 alpha | 96.40% | 85.14% |
| CHEMBL217 | P14416 | Dopamine D2 receptor | 94.36% | 95.62% |
| CHEMBL241 | Q14432 | Phosphodiesterase 3A | 93.93% | 92.94% |
| CHEMBL2581 | P07339 | Cathepsin D | 91.90% | 98.95% |
| CHEMBL2056 | P21728 | Dopamine D1 receptor | 91.15% | 91.00% |
| CHEMBL1293249 | Q13887 | Kruppel-like factor 5 | 90.44% | 86.33% |
| CHEMBL3108638 | O15164 | Transcription intermediary factor 1-alpha | 88.06% | 95.56% |
| CHEMBL225 | P28335 | Serotonin 2c (5-HT2c) receptor | 87.76% | 89.62% |
| CHEMBL3438 | Q05513 | Protein kinase C zeta | 87.71% | 88.48% |
| CHEMBL5697 | Q9GZT9 | Egl nine homolog 1 | 85.13% | 93.40% |
| CHEMBL4203 | Q9HAZ1 | Dual specificity protein kinase CLK4 | 85.00% | 94.45% |
| CHEMBL5608 | Q16288 | NT-3 growth factor receptor | 84.23% | 95.89% |
| CHEMBL5845 | P23415 | Glycine receptor subunit alpha-1 | 82.62% | 90.71% |
| CHEMBL5469 | Q14289 | Protein tyrosine kinase 2 beta | 82.51% | 91.03% |
| CHEMBL2069156 | Q14145 | Kelch-like ECH-associated protein 1 | 81.91% | 82.38% |
| CHEMBL1902 | P62942 | FK506-binding protein 1A | 80.66% | 97.05% |
| CHEMBL2146302 | O94925 | Glutaminase kidney isoform, mitochondrial | 80.56% | 100.00% |
| CHEMBL3060 | Q9Y345 | Glycine transporter 2 | 80.55% | 99.17% |
| CHEMBL1907603 | Q05586 | Glutamate NMDA receptor; GRIN1/GRIN2B | 80.28% | 95.89% |
Below are displayed all the plants proven (via scientific papers) to contain this
compound!
To see more specific details click the taxa you are interested in.
To see more specific details click the taxa you are interested in.
| Croton hemiargyreus |
| PubChem | 163067845 |
| LOTUS | LTS0081378 |
| wikiData | Q104392621 |