methyl (4aS,6aR,6aS,14aS,14bS)-10-hydroxy-6a,6a,9,14a-tetramethyl-2-methylidene-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-4a-carboxylate

Details

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Internal ID 94723289-b40e-4b06-9d6b-06616f05b571
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Carboxylic acid derivatives > Carboxylic acid esters > Methyl esters
IUPAC Name methyl (4aS,6aR,6aS,14aS,14bS)-10-hydroxy-6a,6a,9,14a-tetramethyl-2-methylidene-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-4a-carboxylate
SMILES (Canonical) CC1=C(C(=O)C=C2C1=CC=C3C2(CCC4(C3(CCC5(C4CC(=C)CC5)C(=O)OC)C)C)C)O
SMILES (Isomeric) CC1=C(C(=O)C=C2C1=CC=C3[C@]2(CC[C@@]4([C@@]3(CC[C@@]5([C@H]4CC(=C)CC5)C(=O)OC)C)C)C)O
InChI InChI=1S/C29H36O4/c1-17-9-10-29(25(32)33-6)14-13-27(4)22-8-7-19-18(2)24(31)21(30)16-20(19)26(22,3)11-12-28(27,5)23(29)15-17/h7-8,16,23,31H,1,9-15H2,2-6H3/t23-,26-,27+,28-,29-/m0/s1
InChI Key CPFUJAKVJBYWJA-BTRWLOMLSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C29H36O4
Molecular Weight 448.60 g/mol
Exact Mass 448.26135963 g/mol
Topological Polar Surface Area (TPSA) 63.60 Ų
XlogP 5.00

Synonyms

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SCHEMBL30688054

2D Structure

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2D Structure of methyl (4aS,6aR,6aS,14aS,14bS)-10-hydroxy-6a,6a,9,14a-tetramethyl-2-methylidene-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-4a-carboxylate

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.14% 91.11%
CHEMBL4040 P28482 MAP kinase ERK2 97.47% 83.82%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 94.29% 94.45%
CHEMBL2581 P07339 Cathepsin D 92.22% 98.95%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 91.27% 95.56%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 90.40% 99.23%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 89.46% 96.09%
CHEMBL340 P08684 Cytochrome P450 3A4 88.03% 91.19%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 86.61% 93.03%
CHEMBL5608 Q16288 NT-3 growth factor receptor 84.80% 95.89%
CHEMBL3746 P80365 11-beta-hydroxysteroid dehydrogenase 2 84.61% 94.78%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 83.85% 91.07%
CHEMBL3192 Q9BY41 Histone deacetylase 8 82.65% 93.99%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 82.28% 90.71%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 81.06% 94.33%
CHEMBL241 Q14432 Phosphodiesterase 3A 80.87% 92.94%
CHEMBL1994 P08235 Mineralocorticoid receptor 80.33% 100.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Salacia kraussii

Cross-Links

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PubChem 10411393
LOTUS LTS0074875
wikiData Q104967496