3-O-(alpha-L-oleandrosyl)erythronolide B

Details

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Internal ID 8e5e38f2-67e8-4aa1-8a7e-c7fe4df05cd0
Taxonomy Phenylpropanoids and polyketides > Macrolides and analogues
IUPAC Name (3R,4S,5R,6R,7R,9R,11R,12S,13R,14R)-14-ethyl-6,7,12-trihydroxy-4-[(2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C28H50O10/c1-10-19-14(3)23(30)15(4)22(29)13(2)12-28(8,34)26(32)16(5)25(17(6)27(33)37-19)38-21-11-20(35-9)24(31)18(7)36-21/h13-21,23-26,30-32,34H,10-12H2,1-9H3/t13-,14+,15+,16+,17-,18+,19-,20+,21+,23+,24+,25+,26-,28-/m1/s1
InChI Key JAQMVBAAUKSWIW-DDRSCQIDSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C28H50O10
Molecular Weight 546.70 g/mol
Exact Mass 546.34039779 g/mol
Topological Polar Surface Area (TPSA) 152.00 Ų
XlogP 2.30

Synonyms

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L-oleandrosyl-erythronolide B
3-L-oleandrosyl-erythronolide B
(3R,4S,5R,6R,7R,9R,11R,12S,13R,14R)-14-ethyl-4,6,7,12-tetrahydroxy-3,5,7,9,11,13-hexamethyl-2,10-dioxooxacyclotetradecan-4-yl 2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranoside
(3R,4S,5R,6R,7R,9R,11R,12S,13R,14R)-14-ethyl-6,7,12-trihydroxy-4-{[(2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione
CHEBI:63289
Q27132556
(3R,4S,5R,6R,7R,9R,11R,12S,13R,14R)-14-ethyl-6,7,12-trihydroxy-4-[(2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione

2D Structure

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2D Structure of 3-O-(alpha-L-oleandrosyl)erythronolide B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 96.69% 85.14%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.20% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 94.95% 91.11%
CHEMBL3137262 O60341 LSD1/CoREST complex 94.33% 97.09%
CHEMBL253 P34972 Cannabinoid CB2 receptor 91.16% 97.25%
CHEMBL1293249 Q13887 Kruppel-like factor 5 88.59% 86.33%
CHEMBL226 P30542 Adenosine A1 receptor 86.02% 95.93%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 85.77% 95.56%
CHEMBL241 Q14432 Phosphodiesterase 3A 85.07% 92.94%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 84.87% 92.62%
CHEMBL5255 O00206 Toll-like receptor 4 84.57% 92.50%
CHEMBL5608 Q16288 NT-3 growth factor receptor 84.51% 95.89%
CHEMBL1951 P21397 Monoamine oxidase A 84.44% 91.49%
CHEMBL2581 P07339 Cathepsin D 84.15% 98.95%
CHEMBL1994 P08235 Mineralocorticoid receptor 84.01% 100.00%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 83.36% 94.00%
CHEMBL218 P21554 Cannabinoid CB1 receptor 82.58% 96.61%
CHEMBL1871 P10275 Androgen Receptor 81.62% 96.43%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 81.56% 99.23%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 81.42% 97.14%
CHEMBL1806 P11388 DNA topoisomerase II alpha 81.25% 89.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 10218311
LOTUS LTS0137199
wikiData Q27132556