3-Hydroxy-N-methylwelwitindolinone C isonitrile

Details

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Internal ID f912a259-4c57-4f21-8bf3-828820c100ca
Taxonomy Organoheterocyclic compounds > Indoles and derivatives
IUPAC Name (2S,3S,6R,8S)-4-chloro-3-ethenyl-8-hydroxy-2-isocyano-3,7,7,10-tetramethyl-10-azatetracyclo[6.6.1.12,6.011,15]hexadeca-1(15),4,11,13-tetraene-9,16-dione
SMILES (Canonical) CC1(C2C=C(C(C(C2=O)(C3=C4C1(C(=O)N(C4=CC=C3)C)O)[N+]#[C-])(C)C=C)Cl)C
SMILES (Isomeric) C[C@]1(C(=C[C@H]2C(=O)[C@@]1(C3=C4C(=CC=C3)N(C(=O)[C@@]4(C2(C)C)O)C)[N+]#[C-])Cl)C=C
InChI InChI=1S/C22H21ClN2O3/c1-7-20(4)15(23)11-13-17(26)21(20,24-5)12-9-8-10-14-16(12)22(28,19(13,2)3)18(27)25(14)6/h7-11,13,28H,1H2,2-4,6H3/t13-,20+,21+,22-/m0/s1
InChI Key GFNPBZSGZFQTJA-WOHBTAIZSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C22H21ClN2O3
Molecular Weight 396.90 g/mol
Exact Mass 396.1240702 g/mol
Topological Polar Surface Area (TPSA) 62.00 Ų
XlogP 3.00

Synonyms

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DTXSID001334878
(2aS,4R,7S,8S)-6-Chloro-2a-hydroxy-8-isocyano-1,3,3,7-tetramethyl-7-vinyl-1,2a,3,4,7,8-hexahydro-2H-4,8-methanocyclonona[cd]indole-2,12-dione

2D Structure

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2D Structure of 3-Hydroxy-N-methylwelwitindolinone C isonitrile

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.24% 95.56%
CHEMBL2581 P07339 Cathepsin D 93.92% 98.95%
CHEMBL1293249 Q13887 Kruppel-like factor 5 91.21% 86.33%
CHEMBL217 P14416 Dopamine D2 receptor 91.17% 95.62%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 88.12% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 85.95% 94.45%
CHEMBL2265 P23141 Acyl coenzyme A:cholesterol acyltransferase 84.10% 85.94%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 83.20% 100.00%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 82.53% 82.69%
CHEMBL3401 O75469 Pregnane X receptor 82.36% 94.73%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 81.93% 93.40%
CHEMBL3492 P49721 Proteasome Macropain subunit 81.38% 90.24%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 10786957
LOTUS LTS0202021
wikiData Q75058929